Title : In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective.

Pub. Date : 2013 Nov 25

PMID : 24107266






1 Functional Relationships(s)
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1 We investigated the independent and interactive effects of prenatal exposure to BaP and GSH deficiency due to deletion of the modifier subunit of glutamate cysteine ligase (Gclm), the rate-limiting enzyme in GSH synthesis, on adiposity and hepatic steatosis in adult female F1 offspring. Glutathione glutamate-cysteine ligase, modifier subunit Mus musculus