Tyrosine

mitogen-activated protein kinase 1 ; Homo sapiens







271 Article(s)
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1 34665271 Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3. 2022 Jan 1
2 35197444 Numb-PRRL promotes TGF-β1- and EGF-induced epithelial-to-mesenchymal transition in pancreatic cancer. 2022 Feb 23 1
3 34028590 Tyrosine phosphorylation differentially fine-tunes ionotropic and metabotropic responses of human α7 nicotinic acetylcholine receptor. 2021 Jul 1
4 34046359 Recurrent Somatic MAP2K1 Mutations in Papillary Thyroid Cancer and Colorectal Cancer. 2021 1
5 34157521 Epidermal growth factor receptor and integrins meet redox signaling through P66shc and Rac1. 2021 Oct 1
6 34699606 Zinc induces reactive astrogliosis through ERK-dependent activation of Stat3 and promotes synaptic degeneration. 2021 Dec 2
7 31907582 Cyclosporin A activates human hepatocellular carcinoma (HepG2 cells) proliferation: implication of EGFR-mediated ERK1/2 signaling pathway. 2020 May 1
8 32420725 IL-1β Enhances the Antiviral Effect of IFN-α on HCV Replication by Negatively Modulating ERK2 Activation. 2020 Jul 10 2
9 32655375 CB1 Cannabinoid Receptors Stimulate Gβγ-GRK2-Mediated FAK Phosphorylation at Tyrosine 925 to Regulate ERK Activation Involving Neuronal Focal Adhesions. 2020 13
10 32782566 ERK-mediated negative feedback regulation of oncogenic EGFRvIII in glioblastoma cells. 2020 Sep 1
11 33123602 Hypoxia Impairs NK Cell Cytotoxicity through SHP-1-Mediated Attenuation of STAT3 and ERK Signaling Pathways. 2020 1
12 33133138 Combining PARP and DNA-PK Inhibitors With Irradiation Inhibits HPV-Negative Head and Neck Cancer Squamous Carcinoma Growth. 2020 1
13 33239753 Photosensitive tyrosine analogues unravel site-dependent phosphorylation in TrkA initiated MAPK/ERK signaling. 2020 Nov 25 1
14 30835471 Role of Conserved Histidine and Serine in the HCXXXXXRS Motif of Human Dual-Specificity Phosphatase 5. 2019 Apr 22 1
15 31013829 Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling. 2019 Apr 12 2
16 31053301 Negative feedback regulation of ErbB4 tyrosine kinase activity by ERK-mediated non-canonical phosphorylation. 2019 Jun 25 1
17 31318149 Quantification of the Dynamic Phosphorylation Process of ERK Using Stable Isotope Dilution Selective Reaction Monitoring Mass Spectrometry. 2019 Sep 1
18 31614935 Whole Genome Sequencing of Familial Non-Medullary Thyroid Cancer Identifies Germline Alterations in MAPK/ERK and PI3K/AKT Signaling Pathways. 2019 Oct 13 1
19 29052270 Crystal structure of the human dual specificity phosphatase 1 catalytic domain. 2018 Feb 1
20 30131371 G protein-coupled receptor kinases (GRKs) orchestrate biased agonism at the β2-adrenergic receptor. 2018 Aug 21 2
21 30160357 Sprouty2 suppresses progression and correlates to favourable prognosis of intrahepatic cholangiocarcinoma via antagonizing FGFR2 signalling. 2018 Nov 1
22 27924560 Assaying Activation and Subcellular Localization of ERK in Cells and Tissues. 2017 1
23 27956712 Induction of Integrin Signaling by Steroid Sulfatase in Human Cervical Cancer Cells. 2017 May 1 2
24 28073159 Polymeric immunoglobulin receptor promotes tumor growth in hepatocellular carcinoma. 2017 Jun 1
25 28082684 Absence of IQGAP1 Protein Leads to Insulin Resistance. 2017 Feb 24 1
26 28486761 Panitumumab interaction with TAS-102 leads to combinational anticancer effects via blocking of EGFR-mediated tumor response to trifluridine. 2017 Aug 1
27 28694330 Phosphorylation of the C-Raf N Region Promotes Raf Dimerization. 2017 Oct 1 1
28 28785244 AM-37 and ST-36 Are Small Molecule Bombesin Receptor Antagonists. 2017 1
29 26655221 Molecular Determinants of Kv1.3 Potassium Channels-induced Proliferation. 2016 Feb 12 1
30 26838549 Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation. 2016 Feb 2 1
31 26950759 Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding. 2016 Mar 29 1
32 27339895 Role of WW Domain-containing Oxidoreductase WWOX in Driving T Cell Acute Lymphoblastic Leukemia Maturation. 2016 Aug 12 3
33 27422819 Follicle-Stimulating Hormone (FSH)-dependent Regulation of Extracellular Regulated Kinase (ERK) Phosphorylation by the Mitogen-activated Protein (MAP) Kinase Phosphatase MKP3. 2016 Sep 9 2
34 27793200 Subcellular localisation of pMEK has a different prognosis in locally advanced head and neck cancer treated with concomitant radiochemotherapy. 2016 Oct 28 1
35 25391654 Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells. 2015 Jan 2 1
36 25659802 GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy. 2015 Feb 9 1
37 25730798 An extract of Perilla stem inhibits Src homology phosphatase-1 (SHP)-1 and influences insulin signaling. 2015 Mar 2
38 26031292 Activation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin. 2015 Aug 1
39 26171055 Nitric oxide/cyclic guanosine monophosphate inducers sodium nitroprusside and L-arginine inhibit the proliferation of gastric cancer cells via the activation of type II cyclic guanosine monophosphate-dependent protein kinase. 2015 Jul 3
40 26235103 Detection and Differentiation of Threonine- and Tyrosine-Monophosphorylated Forms of ERK1/2 by Capillary Isoelectric Focusing-Immunoassay. 2015 Aug 3 1
41 26286528 Identification of inhibitors that target dual-specificity phosphatase 5 provide new insights into the binding requirements for the two phosphate pockets. 2015 Aug 19 1
42 26680585 ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation. 2015 Dec 1
43 23563275 Ability of the new AT1 receptor blocker azilsartan to block angiotensin II-induced AT1 receptor activation after wash-out. 2014 Mar 1
44 24809457 Galectin-3 induces cell migration via a calcium-sensitive MAPK/ERK1/2 pathway. 2014 Apr 30 1
45 24844603 Extracellular signal-regulated protein kinases 1 and 2 activation by addictive drugs: a signal toward pathological adaptation. 2014 Dec 15 1
46 23319303 Proteomic analysis of novel targets associated with TrkA-mediated tyrosine phosphorylation signaling pathways in SK-N-MC neuroblastoma cells. 2013 Jan 2
47 23528948 A quantitative model of ERK MAP kinase phosphorylation in crowded media. 2013 1
48 23575685 Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. 2013 1
49 23659921 Differential role of Dok1 and Dok2 in TLR2-induced inflammatory signaling in glia. 2013 Sep 1
50 23822636 Inverse correlation between Thr-669 and constitutive tyrosine phosphorylation in the asymmetric epidermal growth factor receptor dimer conformation. 2013 Oct 2