Pub. Date : 2020 Sep
PMID : 32782566
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The present study indicated that activation of the MEK-ERK pathway led to the phosphorylation of Thr-402, a conserved negative feedback residue in the juxtamembrane domain corresponding to Thr-669 of wild-type EGFR (EGFRwt), which resulted in a rapid reduction in the tyrosine phosphorylation of EGFRvIII in U87MG human glioblastoma and 293 cells. | Tyrosine | mitogen-activated protein kinase 1 | Homo sapiens |