Tyrosine

mitogen-activated protein kinase 1 ; Homo sapiens







271 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 23874979 ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells. 2013 1
52 23876235 Global characterization of signalling networks associated with tamoxifen resistance in breast cancer. 2013 Nov 1
53 23883624 Phospholipase C-γ2 via p38 and ERK1/2 MAP kinase mediates diperoxovanadate-asparagine induced human platelet aggregation and sCD40L release. 2013 1
54 24751667 Incorporation of ortho- and meta-tyrosine into cellular proteins leads to erythropoietin-resistance in an erythroid cell line. 2013 1
55 21933022 Transcriptional repression of Mad-Max complex by human umbilical cord blood stem cells downregulates extracellular signal-regulated kinase in glioblastoma. 2012 Jul 1 1
56 22121028 Phos-tag SDS-PAGE systems for phosphorylation profiling of proteins with a wide range of molecular masses under neutral pH conditions. 2012 Jan 1
57 22235371 Extracellular Signal-Regulated Kinase (ERK) Activation and Mitogen-Activated Protein Kinase Phosphatase 1 Induction by Pulsatile Gonadotropin-Releasing Hormone in Pituitary Gonadotrophs. 2012 4
58 22238675 Trihydrophobin 1 phosphorylation by c-Src regulates MAPK/ERK signaling and cell migration. 2012 2
59 22260695 ERK phosphorylation and nuclear accumulation: insights from single-cell imaging. 2012 Feb 2
60 22305891 Tyrosines 303/343/353 within the Sprouty-related domain of Spred2 are essential for its interaction with p85 and inhibitory effect on Ras/ERK activation. 2012 May 2
61 22327338 c-ABL modulates MAP kinases activation downstream of VEGFR-2 signaling by direct phosphorylation of the adaptor proteins GRB2 and NCK1. 2012 Jun 2
62 22481092 Paxillin phosphorylation and complexing with Erk and FAK are regulated by PLD activity in MDA-MB-231 cells. 2012 Aug 1
63 22521882 Global tyrosine kinome profiling of human thyroid tumors identifies Src as a promising target for invasive cancers. 2012 May 11 1
64 22581436 PYK-2 is tyrosine phosphorylated after activation of pituitary adenylate cyclase activating polypeptide receptors in lung cancer cells. 2012 Nov 1
65 22833667 Integrin α2β1 mediates tyrosine phosphorylation of vascular endothelial cadherin induced by invasive breast cancer cells. 2012 Sep 21 1
66 22851227 Participation of Gab1 and Gab2 in IL-22-mediated keratinocyte proliferation, migration, and differentiation. 2012 Oct 1
67 23071622 Quantitative phosphoproteomics reveals SLP-76 dependent regulation of PAG and Src family kinases in T cells. 2012 1
68 21531714 Sprouty-related Ena/vasodilator-stimulated phosphoprotein homology 1-domain-containing protein (SPRED1), a tyrosine-protein phosphatase non-receptor type 11 (SHP2) substrate in the Ras/extracellular signal-regulated kinase (ERK) pathway. 2011 Jul 1 2
69 21813649 Cyclin-dependent kinase-5 is a key molecule in tumor necrosis factor-α-induced insulin resistance. 2011 Sep 23 1
70 19826412 Shc is required for ErbB2-induced inhibition of apoptosis but is dispensable for cell proliferation and disruption of cell polarity. 2010 Jan 14 1
71 20592309 Extracellular signal-regulated kinases (ERKs) pathway and reactive oxygen species regulate tyrosine phosphorylation in capacitating boar spermatozoa. 2010 Nov 2
72 20623096 New concepts in phospholipase D signaling in inflammation and cancer. 2010 Jul 7 1
73 19167484 Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity. 2009 May 1
74 19305428 The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants. 2009 Apr 23 1
75 19410646 Novel phosphotyrosine targets of FGFR2IIIb signaling. 2009 Sep 1
76 19457093 Inhibition of EGF-induced ERK/MAP kinase-mediated astrocyte proliferation by mu opioids: integration of G protein and beta-arrestin 2-dependent pathways. 2009 Jul 2
77 19509291 GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through the activation of extracellular signal-regulated kinase signaling. 2009 Jul 24 2
78 19559020 A reduction of epidermal growth factor receptor is involved in brefelamide-induced inhibition of phosphorylation of ERK in human astrocytoma cells. 2009 Aug 15 1
79 19665053 Gab1 transduces PI3K-mediated erythropoietin signals to the Erk pathway and regulates erythropoietin-dependent proliferation and survival of erythroid cells. 2009 Dec 1
80 19804359 EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells. 2009 Dec 1
81 18182379 FAK-mediated activation of ERK for eosinophil migration: a novel mechanism for infection-induced allergic inflammation. 2008 Mar 2
82 18263590 Interaction between ERK and GSK3beta mediates basic fibroblast growth factor-induced apoptosis in SK-N-MC neuroblastoma cells. 2008 Apr 4 3
83 18280112 DUSP6/MKP-3 inactivates ERK1/2 but fails to bind and inactivate ERK5. 2008 May 1
84 18400991 Repetitive deformation activates Src-independent FAK-dependent ERK motogenic signals in human Caco-2 intestinal epithelial cells. 2008 Jun 2
85 18460189 Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium. 2008 May 6 1
86 18540849 Culture of human A375 melanoma cells in the presence of fibronectin causes expression of MMP-9 and activation of MMP-2 in culture supernatants. 2008 1
87 18720373 Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5. 2008 Dec 2
88 18762250 ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling. 2008 Nov 1
89 18922979 Focal adhesion kinase controls aggressive phenotype of androgen-independent prostate cancer. 2008 Oct 1
90 17088251 Repetitive deformation activates focal adhesion kinase and ERK mitogenic signals in human Caco-2 intestinal epithelial cells through Src and Rac1. 2007 Jan 5 1
91 17285175 The synthesis of phosphopeptides via the Bpoc-based approach. 2007 Feb 21 1
92 17367757 The carboxyl terminal tyrosine 417 residue of NOK has an autoinhibitory effect on NOK-mediated signaling transductions. 2007 May 4 2
93 17597065 Role of non-phosphorylated activation loop residues in determining ERK2 dephosphorylation, activity, and subcellular localization. 2007 Aug 24 3
94 17620366 Extracellular signal-regulated kinase activation during renal ischemia/reperfusion mediates focal adhesion dissolution and renal injury. 2007 Aug 1
95 17717636 Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer. 2007 Dec 1
96 17785202 FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway. 2007 Sep 2
97 15935618 Oncostatin M-induced activation of stress-activated MAP kinases depends on tyrosine 861 in the OSM receptor and requires Jak1 but not Src kinases. 2006 Jan 2
98 16197369 Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells. 2006 Feb 1 1
99 16250012 Tyrosine phosphatase SHP-2 regulates IL-1 signaling in fibroblasts through focal adhesions. 2006 Apr 1
100 16461767 Integrin alpha2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: identification of a novel signaling pathway. 2006 Mar 31 1