Title : Sprouty2 suppresses progression and correlates to favourable prognosis of intrahepatic cholangiocarcinoma via antagonizing FGFR2 signalling.

Pub. Date : 2018 Nov

PMID : 30160357






1 Functional Relationships(s)
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1 By overexpressing SPRY2-wide type or SPRY2-Y55F, the tyrosine-55 of SPRY2 was demonstrated to be essential in suppressing ERK phosphorylation, tumour invasion and EMT of ICC cells. Tyrosine mitogen-activated protein kinase 1 Homo sapiens