Pub. Date : 2018 Aug 21
PMID : 30131371
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We showed that an alanine mutant of the highly conserved residue tyrosine 219 (Y219A) in transmembrane domain five of the beta2-adrenergic receptor (beta2AR) was incapable of beta-arrestin recruitment, receptor internalization, and beta-arrestin-mediated activation of extracellular signal-regulated kinase (ERK), whereas it retained the ability to signal through G protein. | Tyrosine | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | We showed that an alanine mutant of the highly conserved residue tyrosine 219 (Y219A) in transmembrane domain five of the beta2-adrenergic receptor (beta2AR) was incapable of beta-arrestin recruitment, receptor internalization, and beta-arrestin-mediated activation of extracellular signal-regulated kinase (ERK), whereas it retained the ability to signal through G protein. | Tyrosine | mitogen-activated protein kinase 1 | Homo sapiens |