Title : Drug-induced alterations in the extracellular signal-regulated kinase (ERK) signalling pathway: implications for reinforcement and reinstatement.

Pub. Date : 2008 Feb

PMID : 18041576






2 Functional Relationships(s)
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1 Here, we review previous literatures that focus on the effects of exposure to cocaine, amphetamine, Delta(9)-tetrahydrocannabinol (THC), nicotine, morphine, and alcohol on ERK signaling in the mesocorticolimbic dopamine system; these alterations of ERK signaling have been thought to contribute to the drug"s rewarding effects and to the long-term maladaptation induced by drug abuse. Nicotine mitogen-activated protein kinase 1 Homo sapiens
2 Here, we review previous literatures that focus on the effects of exposure to cocaine, amphetamine, Delta(9)-tetrahydrocannabinol (THC), nicotine, morphine, and alcohol on ERK signaling in the mesocorticolimbic dopamine system; these alterations of ERK signaling have been thought to contribute to the drug"s rewarding effects and to the long-term maladaptation induced by drug abuse. Nicotine mitogen-activated protein kinase 1 Homo sapiens