| 51 |
14757755 | Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. | 2004 Feb 2 |
2 |
| 52 |
12446733 | The requirement of specific membrane domains for Raf-1 phosphorylation and activation. | 2003 Jan 31 |
2 |
| 53 |
12469113 | Structure and regulation of the cAMP-binding domains of Epac2. | 2003 Jan |
1 |
| 54 |
12508104 | Cellular functions of the Rap1 GTP-binding protein: a pattern emerges. | 2003 Feb 1 |
1 |
| 55 |
13679863 | Rap1A and rap1B ras-family proteins are prominently expressed in the nucleus of squamous carcinomas: nuclear translocation of GTP-bound active form. | 2003 Sep 18 |
5 |
| 56 |
11788480 | Cyclic AMP raises intracellular Ca(2+) in human megakaryocytes independent of protein kinase A. | 2002 Jan |
1 |
| 57 |
12171996 | The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated cell adhesion. | 2002 Aug 16 |
1 |
| 58 |
12186953 | Evidence for a role for the Dictyostelium Rap1 in cell viability and the response to osmotic stress. | 2002 Sep 15 |
1 |
| 59 |
11022048 | Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras. | 2001 Jan 26 |
1 |
| 60 |
11266512 | Analysis of the role of the mitogen-activated protein kinase in mediating cyclic-adenosine 3',5'-monophosphate effects on prolactin promoter activity. | 2001 Apr |
1 |
| 61 |
10753869 | Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL. | 2000 Apr 14 |
1 |
| 62 |
10835426 | CalDAG-GEFIII activation of Ras, R-ras, and Rap1. | 2000 Aug 18 |
1 |
| 63 |
10861233 | Low-density lipoprotein activates the small GTPases Rap1 and Ral in human platelets. | 2000 Jul 1 |
1 |
| 64 |
10913189 | Rap2 as a slowly responding molecular switch in the Rap1 signaling cascade. | 2000 Aug |
2 |
| 65 |
10934204 | Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction. | 2000 Nov 10 |
1 |
| 66 |
10962559 | Quantitative determination of Rap 1 activation in cyclic nucleotide-treated HL-60 leukemic cells: lack of Rap 1 activation in variant cells. | 2000 Aug 17 |
1 |
| 67 |
10982853 | c-Src signaling induced by the adapters Sin and Cas is mediated by Rap1 GTPase. | 2000 Oct |
1 |
| 68 |
9882515 | RAP1A GTP/GDP cycles determine the intracellular location of the late endocytic compartments and contribute to myogenic differentiation. | 1999 Jan 10 |
3 |
| 69 |
10318861 | Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504. | 1999 May 14 |
1 |
| 70 |
10593970 | Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk. | 1999 Dec 17 |
2 |
| 71 |
10608844 | RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans. | 1999 Dec 31 |
3 |
| 72 |
9478939 | Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes. | 1998 Feb 27 |
2 |
| 73 |
9564038 | Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes. | 1998 May 1 |
1 |
| 74 |
9843482 | All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral. | 1998 Dec 1 |
1 |
| 75 |
9853756 | Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. | 1998 Dec 3 |
1 |
| 76 |
9029146 | Rapid Ca2+-mediated activation of Rap1 in human platelets. | 1997 Jan 15 |
1 |
| 77 |
9102473 | The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+. | 1997 Mar 7 |
1 |
| 78 |
9311917 | Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1. | 1997 Oct 3 |
3 |
| 79 |
8636102 | Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor. | 1996 Mar 22 |
1 |
| 80 |
8832375 | Oncogenic amino acid substitutions in the inhibitory rap-1A protein cause it to adopt a ras-p21-like conformation as computed using molecular dynamics. | 1996 Jun |
1 |
| 81 |
8838585 | Prediction of the three-dimensional structure of the rap-1A protein from its homology to the ras-gene-encoded p21 protein. | 1996 Jan |
3 |
| 82 |
8900189 | SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase. | 1996 Oct 25 |
1 |
| 83 |
9145335 | Differential expression of protein kinase C isozymes and small GTP-binding proteins during HL60 cell differentiation by retinoic acid and cyclic AMP: relation with phospholipase D (PLD) activation. | 1996-1997 |
1 |
| 84 |
7479768 | Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family. | 1995 Oct 24 |
1 |
| 85 |
7498475 | rap1 p21 regulates the interaction of ras p21 with RGL, a new effector protein of ras p21. | 1995 Nov 13 |
2 |
| 86 |
7737967 | Cyclic AMP-dependent activation of Rap1b. | 1995 May 5 |
1 |
| 87 |
7791872 | The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue. | 1995 Jun 15 |
1 |
| 88 |
7833480 | Function of wild-type or mutant Rac2 and Rap1a GTPases in differentiated HL60 cell NADPH oxidase activation. | 1995 Feb 1 |
2 |
| 89 |
8524135 | Purification of human neutrophil NADPH oxidase cytochrome b-558 and association with Rap 1A. | 1995 |
2 |
| 90 |
7803284 | Ultrastructural localization of the small GTP-binding protein Rap1 in human platelets and megakaryocytes. | 1994 Oct |
1 |
| 91 |
7980444 | SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism. | 1994 Nov 1 |
1 |
| 92 |
8034626 | Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes. | 1994 Jul 22 |
4 |
| 93 |
8048970 | Phosphorylation of Rap1GAP during the cell cycle. | 1994 Jul 29 |
1 |
| 94 |
8216264 | The Rap1A protein enhances protein kinase C activity in vitro. | 1993 Sep 30 |
1 |
| 95 |
1310590 | Evidence for a role of rap1 protein in the regulation of human platelet Ca2+ fluxes. | 1992 Jan 15 |
1 |
| 96 |
1730690 | Asparagine 26, glutamic acid 31, valine 45, and tyrosine 64 of Ras proteins are required for their oncogenicity. | 1992 Jan 25 |
1 |
| 97 |
1763330 | Inhibition of Rap1A binding to cytochrome b558 of NADPH oxidase by phosphorylation of Rap1A. | 1991 Dec 20 |
2 |
| 98 |
1773804 | Genetic analysis of the K-rev-1 transformation-suppressor gene. | 1991 Jun |
1 |
| 99 |
1828804 | The residues of Ras and Rap proteins that determine their GAP specificities. | 1991 Jun 25 |
1 |
| 100 |
1900291 | Antisera specific for rap 1 proteins distinguish between processed and nonprocessed rap 1b. | 1991 Mar 5 |
6 |