Title : Quantitative determination of Rap 1 activation in cyclic nucleotide-treated HL-60 leukemic cells: lack of Rap 1 activation in variant cells.

Pub. Date : 2000 Aug 17

PMID : 10962559






1 Functional Relationships(s)
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1 We have now developed an enzyme-based method for assessing Rap 1 activation which is quantitative and provides a measurement of the per cent of Rap molecules in the active GTP-bound state. Guanosine Triphosphate RAP1A, member of RAS oncogene family Homo sapiens