Title : T-2 toxin is a cytochrome P450 1A1 inducer and leads to MAPK/p38- but not aryl hydrocarbon receptor-dependent interleukin-8 secretion in the human intestinal epithelial cell line Caco-2.

Pub. Date : 2011 Jun 18

PMID : 21453744






1 Functional Relationships(s)
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Protein Name
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1 Like benzo-[a]-pyrene (B[a]P), a well known AHR ligand, T-2 led to cytochrome P450 1A1 (CYP1A1) mRNA expression in Caco-2 cells, which could be inhibited by the AHR antagonist resveratrol. Benzo(a)pyrene aryl hydrocarbon receptor Homo sapiens