Benzo(a)pyrene

aryl hydrocarbon receptor ; Homo sapiens







148 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34906874 High throughput data-based, toxicity pathway-oriented development of a quantitative adverse outcome pathway network linking AHR activation to lung damages. 2022 Mar 5 2
2 35624854 Antioxidant Activities and Mechanisms of Tomentosin in Human Keratinocytes. 2022 May 18 2
3 33278487 Comparison of quantitation methods in proteomics to define relevant toxicological information on AhR activation of HepG2 cells by BaP. 2021 Jan 30 1
4 33288249 Aryl hydrocarbon receptor mediates benzo[a]pyrene-induced metabolic reprogramming in human lung epithelial BEAS-2B cells. 2021 Feb 20 10
5 33429317 Benzo[a]pyrene induces fibrotic changes and impairs differentiation in lung stem cells. 2021 Mar 1 3
6 33790107 The Differential Selectivity of Aryl Hydrocarbon Receptor (AHR) Agonists towards AHR-Dependent Suppression of Mammosphere Formation and Gene Transcription in Human Breast Cancer Cells. 2021 1
7 33936062 Benzo(a)pyrene Enhanced Dermatophagoides Group 1 (Der f 1)-Induced TGFβ1 Signaling Activation Through the Aryl Hydrocarbon Receptor-RhoA Axis in Asthma. 2021 4
8 34065697 Quercetin and Isorhamnetin Attenuate Benzo[a]pyrene-Induced Toxicity by Modulating Detoxification Enzymes through the AhR and NRF2 Signaling Pathways. 2021 May 16 1
9 34122006 Oral Administration of Brain Protein Combined With Probiotics Induces Immune Tolerance Through the Tryptophan Pathway. 2021 2
10 34439562 Curcumin Suppresses the Lipid Accumulation and Oxidative Stress Induced by Benzo[a]pyrene Toxicity in HepG2 Cells. 2021 Aug 20 2
11 34690024 Polycyclic aromatic hydrocarbons regulate the pigmentation pathway and induce DNA damage responses in keratinocytes, a process driven by systemic immunity. 2021 Nov 1
12 34944003 Inhibition of Human Osteoclast Differentiation by Kynurenine through the Aryl-Hydrocarbon Receptor Pathway. 2021 Dec 10 1
13 31730885 In vitro and in vivo approaches for identifying the role of aryl hydrocarbon receptor in the development of nonalcoholic fatty liver disease. 2020 Feb 1 5
14 31748929 Down-regulation of aryl hydrocarbon receptor intensifies carcinogen-induced retinal lesion via SOCS3-STAT3 signaling. 2020 Jun 2
15 32166782 Benzo[a]pyrene at human blood equivalent level induces human lung epithelial cell invasion and migration via aryl hydrocarbon receptor signaling. 2020 Aug 1
16 32409577 Dissociation of the AhR/ARNT complex by TGF-β/Smad signaling represses CYP1A1 gene expression and inhibits benze[a]pyrene-mediated cytotoxicity. 2020 Jul 3 6
17 32522345 Genotoxicant exposure, activation of the aryl hydrocarbon receptor, and lipid peroxidation in cultured human alveolar type II A549 cells. 2020 May 1
18 32526964 Baicalein Inhibits Benzo[a]pyrene-Induced Toxic Response by Downregulating Src Phosphorylation and by Upregulating NRF2-HMOX1 System. 2020 Jun 9 7
19 32554009 In vitro profiling of the potential endocrine disrupting activities affecting steroid and aryl hydrocarbon receptors of compounds and mixtures prevalent in human drinking water resources. 2020 Nov 2
20 32557721 Activation of aryl hydrocarbon receptor by benzo[a]pyrene increases interleukin 33 expression and eosinophil infiltration in a mouse model of allergic airway inflammation. 2020 Nov 1
21 32670863 Long-Term Exposure of Early-Transformed Human Mammary Cells to Low Doses of Benzo[a]pyrene and/or Bisphenol A Enhances Their Cancerous Phenotype via an AhR/GPR30 Interplay. 2020 4
22 33349622 Dietary and environmental factors have opposite AhR-dependent effects on C. elegans healthspan. 2020 Dec 13 1
23 30204910 Down-Regulation of p23 in Normal Lung Epithelial Cells Reduces Toxicities From Exposure to Benzo[a]pyrene and Cigarette Smoke Condensate via an Aryl Hydrocarbon Receptor-Dependent Mechanism. 2019 Jan 1 2
24 30748024 Direct activation of aryl hydrocarbon receptor by benzo[a]pyrene elicits T-helper 2-driven proinflammatory responses in a mouse model of allergic dermatitis. 2019 Jul 3
25 30850589 The Aryl hydrocarbon receptor mediates tobacco-induced PD-L1 expression and is associated with response to immunotherapy. 2019 Mar 8 5
26 31051210 Use of in vitro bioassays to facilitate read-across assessment of nitrogen substituted heterocycle analogues of polycyclic aromatic hydrocarbons. 2019 Sep 1
27 31092429 Diallyl Trisulfide Enhances Benzo[a]pyrene-induced CYP1A1 Expression and Metabolic Activation in Hepatic HepG2 Cells. 2019 May 6
28 31111189 The Toll-like receptor agonist imiquimod is metabolized by aryl hydrocarbon receptor-regulated cytochrome P450 enzymes in human keratinocytes and mouse liver. 2019 Jul 4
29 31114548 Protective Effect of Resveratrol on Benzo(a)Pyrene Induced Dysfunctions of Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in Leydig Cells. 2019 2
30 31176714 Expression of Serpin Peptidase Inhibitor B2 (SERPINB2) is regulated by Aryl hydrocarbon receptor (AhR). 2019 Aug 25 4
31 31255691 Comparative mechanisms of PAH toxicity by benzo[a]pyrene and dibenzo[def,p]chrysene in primary human bronchial epithelial cells cultured at air-liquid interface. 2019 Sep 15 1
32 31328511 Newly Identified AhR-Active Compounds in the Sediments of an Industrial Area Using Effect-Directed Analysis. 2019 Sep 3 1
33 31462083 Aryl Hydrocarbon Receptor Mediates Cell Proliferation Enhanced by Benzo[a]pyrene in Human Lung Cancer 3D Spheroids. 2019 5
34 31885779 Antagonizing Effects of Clematis apiifolia DC. Extract against Benzo[a]pyrene-Induced Damage to Human Keratinocytes. 2019 2
35 28782227 Short androgen receptor poly-glutamine-promoted endometrial cancer is associated with benzo[a]pyrene-mediated aryl hydrocarbon receptor activation. 2018 Jan 1
36 29301444 The search of CAR, AhR, ESRs binding sites in promoters of intronic and intergenic microRNAs. 2018 Feb 4
37 29320557 High AHR expression in breast tumors correlates with expression of genes from several signaling pathways namely inflammation and endogenous tryptophan metabolism. 2018 3
38 29545172 Benzo[a]pyrene activates an AhR/Src/ERK axis that contributes to CYP1A1 induction and stable DNA adducts formation in lung cells. 2018 Jun 1 1
39 29643980 Perillaldehyde Inhibits AHR Signaling and Activates NRF2 Antioxidant Pathway in Human Keratinocytes. 2018 2
40 29704546 Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands. 2018 Aug 1
41 29921510 The regulation mechanism of AhR activated by benzo[a]pyrene for CYP expression are different between 2D and 3D culture of human lung cancer cells. 2018 Aug 1
42 30094095 Aryl hydrocarbon receptor activated by benzo (a) pyrene promotes SMARCA6 expression in NSCLC. 2018 1
43 30137621 Aryl Hydrocarbon Receptor-Dependent Metabolism Plays a Significant Role in Estrogen-Like Effects of Polycyclic Aromatic Hydrocarbons on Cell Proliferation. 2018 Oct 1 1
44 27720465 Inhibition of aryl hydrocarbon receptor signaling and induction of NRF2-mediated antioxidant activity by cinnamaldehyde in human keratinocytes. 2017 Jan 1
45 27810545 Assessment of potential biological activities and distributions of endocrine-disrupting chemicals in sediments of the west coast of South Korea. 2017 Feb 1
46 28249752 Benzo[a]pyrene impedes self-renewal and differentiation of mesenchymal stem cells and influences fracture healing. 2017 Jun 1 2
47 28351761 Interleukin-24 as a target cytokine of environmental aryl hydrocarbon receptor agonist exposure in the lung. 2017 Jun 1 2
48 28405246 Modulation of benzo[a]pyrene-DNA adduct formation by CYP1 inducer and inhibitor. 2017 2
49 28461126 Benzo[a]pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytes. 2017 Aug 1 4
50 28676325 Involvement of aryl hydrocarbon receptor (AhR) in polyphenol inhibition of benzo[a]pyrene-induced oxidative stress and neoplastic transformation. 2017 Sep 2