Ammonia

glutamate-ammonia ligase ; Rattus norvegicus







60 Article(s)
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1 27580850 In vivo N-15 MRS study of glutamate metabolism in the rat brain. 2017 Jul 15 2
2 27764760 Artesunate restores spatial learning of rats with hepatic encephalopathy by inhibiting ammonia-induced oxidative damage in neurons and dysfunction of glutamate signaling in astroglial cells. 2016 Dec 1
3 25196365 Assessment of glutamine synthetase activity by [13N]ammonia uptake in living rat brain. 2015 Jan 2
4 25338921 Delivery of glutamine synthetase gene by baculovirus vectors: a proof of concept for the treatment of acute hyperammonemia. 2015 Jan 1
5 26220375 Effects of site-specific infusions of methionine sulfoximine on the temporal progression of seizures in a rat model of mesial temporal lobe epilepsy. 2015 Sep 1
6 26817210 Alpha-Mangostin Partially Preserves Expression of Ammonia-Metabolizing Enzymes in Thioacetamide-Induced Fibrotic and Cirrhotic Rats. 2015 Oct 1
7 24292976 O-GlcNAcylation as a novel ammonia-induced posttranslational protein modification in cultured rat astrocytes. 2014 Dec 1
8 24346692 Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats. 2014 Mar 2
9 24755687 Acute liver failure in rats activates glutamine-glutamate cycle but declines antioxidant enzymes to induce oxidative stress in cerebral cortex and cerebellum. 2014 3
10 25106624 Differential up-regulation of ammonia detoxifying enzymes in cerebral cortex, cerebellum, hippocampus, striatum and liver in hyperammonemia. 2014 1
11 23673435 Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures. 2013 Aug 1
12 22167234 Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized (1)H and (15)N NMR spectroscopy. 2012 Apr 1
13 22618691 The role of glutamine synthetase and glutamate dehydrogenase in cerebral ammonia homeostasis. 2012 Nov 2
14 21193003 Down-regulation of glutamine synthetase enhances migration of rat astrocytes after in vitro injury. 2011 Feb 1
15 21780187 Redistribution of astrocytic glutamine synthetase in the hippocampus of chronic epileptic rats. 2011 Nov 1
16 20689060 Colon luminal content and epithelial cell morphology are markedly modified in rats fed with a high-protein diet. 2010 Nov 1
17 16530878 Direct molecular and spectroscopic evidence for increased ammonia removal capacity of skeletal muscle in acute liver failure. 2006 Jun 4
18 15830392 Lipopolysaccharide-induced tyrosine nitration and inactivation of hepatic glutamine synthetase in the rat. 2005 May 2
19 15923062 Metabolism of [13N]ammonia in rat lung. 2005 Jul 1
20 15114044 Contribution of glutamine synthetase to ammonia-induced apoptosis in gastric mucosal cells. 2004 5
21 15326614 Role of ammonia in reversal of glutamate-mediated Müller cell swelling in the rat retina. 2004 Oct 1
22 12579527 Effect of arginine, ornithine and citrulline supplementation upon performance and metabolism of trained rats. 2003 Mar 1
23 12742096 Glutamine synthetase activity and glutamine content in brain: modulation by NMDA receptors and nitric oxide. 2003 Sep-Oct 1
24 11923223 Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes. 2002 May 1
25 11746427 Ammonia induces the mitochondrial permeability transition in primary cultures of rat astrocytes. 2001 Dec 1 1
26 10429966 High protein diet induces pericentral glutamate dehydrogenase and ornithine aminotransferase to provide sufficient glutamate for pericentral detoxification of ammonia in rat liver lobules. 1999 Jun 2
27 10850554 Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle. 1999 Dec 1
28 9538946 Conditioned medium from cultured rat hepatocytes completely blocks induction of glutamine synthetase by dexamethasone in several rat liver epithelial cell lines. 1998 Feb 1
29 9752723 Regulation of the spatiotemporal pattern of expression of the glutamine synthetase gene. 1998 1
30 9829169 Glutamine synthetase expression and activity are regulated by 3,5,3'-triodo-L-thyronine and hydrocortisone in rat oligodendrocyte cultures. 1998 Aug 1
31 9107685 FISH mapping of three ammonia metabolism genes (Glul, Cps1, Glud1) in rat, and the chromosomal localization of GLUL in human and Cps1 in mouse. 1997 May 1
32 9122259 In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling. 1997 Mar 18 1
33 9331509 An attempt to add biological functions by genetic engineering in order to produce high-performance bioreactor cells for hybrid artificial liver: transfection of glutamine synthetase into Chinese hamster ovary (CHO) cell. 1997 Sep-Oct 1
34 9336301 Treatment of cirrhotic rats with L-ornithine-L-aspartate enhances urea synthesis and lowers serum ammonia levels. 1997 Oct 2
35 9435573 Glutamine synthetase gene expression in the lungs of endotoxin-treated and adrenalectomized rats. 1997 Dec 1
36 9053810 Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat. 1996 Mar 2
37 7487913 Dependence of in vivo glutamine synthetase activity on ammonia concentration in rat brain studied by 1H - 15N heteronuclear multiple-quantum coherence-transfer NMR. 1995 Oct 15 4
38 7910379 Effects of Ca(II) ions on Mn(II) dynamics in chick glia and rat astrocytes: potential regulation of glutamine synthetase. 1994 Feb 1
39 7915704 Changes in distribution and activity of glutamine synthetase in carbon tetrachloride-induced cirrhosis in the rat: potential role in hyperammonemia. 1994 Sep 2
40 8188174 Ammonia-induced brain edema and intracranial hypertension in rats after portacaval anastomosis. 1994 Jun 1
41 7910653 Region-selective reductions in activities of glutamine synthetase in rat brain following portacaval anastomosis. 1993 Dec 1
42 8102050 15N n.m.r. measurement of the in vivo rate of glutamine synthesis and utilization at steady state in the brain of the hyperammonaemic rat. 1993 Jul 15 2
43 8436955 Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy. 1993 Mar 1
44 1363168 Light and electron microscopic immunocytochemical localization of glutamine synthetase in the superficial pineal gland of the rat. 1992 1
45 1671539 Reduction of glutamine synthetase activity in astroglia exposed in culture to low levels of inorganic lead. 1991 Jan 1
46 1674354 Cloning and functional characterization of the rat glutamine synthetase gene. 1991 Feb 1
47 1681554 Methionine sulfoximine intensifies cancer anorexia. 1991 May 3
48 2007367 Pancreatic hepatocytes. An in vivo model for cell lineage in pancreas of adult rat. 1991 Apr 1
49 1982483 Glutamine synthetase inhibition prevents cerebral oedema during hyperammonemia. 1990 1
50 2757524 DNA synthesis in Alzheimer type II astrocytosis. The question of astrocytic proliferation and mitosis in experimentally induced hepatic encephalopathy. 1989 Aug 1