Title : An attempt to add biological functions by genetic engineering in order to produce high-performance bioreactor cells for hybrid artificial liver: transfection of glutamine synthetase into Chinese hamster ovary (CHO) cell.

Pub. Date : 1997 Sep-Oct

PMID : 9331509






1 Functional Relationships(s)
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1 With the aim of adding lost or deficient functions and producing cell lines for the bioreactor of a hybrid artificial liver, rat glutamine synthetase (GS) gene was transfected into Chinese hamster ovary (CHO) cells, because it is able to lower the ammonia level. Ammonia glutamate-ammonia ligase Rattus norvegicus