Title : High protein diet induces pericentral glutamate dehydrogenase and ornithine aminotransferase to provide sufficient glutamate for pericentral detoxification of ammonia in rat liver lobules.

Pub. Date : 1999 Jun

PMID : 10429966






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Free ammonia, that is not converted periportally, is efficiently detoxified in the small rim of hepatocytes around the central veins by glutamine synthetase preventing it from entering the systemic circulation. Ammonia glutamate-ammonia ligase Rattus norvegicus
2 Detoxification of ammonia by glutamine synthetase may be limited due to a shortage of glutamate when the nitrogen load is high. Ammonia glutamate-ammonia ligase Rattus norvegicus