Fluorouracil

nuclear factor kappa B subunit 1 ; Homo sapiens







66 Article(s)
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1 35320055 Signaling Pathways Involved in 5-FU Drug Resistance in Cancer. 2022 Jul 1
2 34502219 S-Adenosylmethionine Increases the Sensitivity of Human Colorectal Cancer Cells to 5-Fluorouracil by Inhibiting P-Glycoprotein Expression and NF-κB Activation. 2021 Aug 27 3
3 34795760 Nrf3 Promotes 5-FU Resistance in Colorectal Cancer Cells via the NF-κB/BCL-2 Signaling Pathway In Vitro and In Vivo. 2021 4
4 34857985 Protective effects of resveratrol against 5-fluorouracil-induced oxidative stress and inflammatory responses in human keratinocytes. 2021 Nov 1
5 31401369 Modulation of 5-fluorouracil activation of toll-like/MyD88/NF-κB/MAPK pathway by Saccharomyces boulardii CNCM I-745 probiotic. 2020 Jan 1
6 31897166 Oxymatrine reverses 5-fluorouracil resistance by inhibition of colon cancer cell epithelial-mesenchymal transition and NF-κB signaling in vitro. 2020 Jan 3
7 32122395 New uracil analog U-332 is an inhibitor of NF-κB in 5-fluorouracil-resistant human leukemia HL-60 cell line. 2020 Mar 2 2
8 32328199 Synergistic Effects of Curcumin and 5-Fluorouracil on the Hepatocellular Carcinoma In vivo and vitro through regulating the expression of COX-2 and NF-κB. 2020 1
9 32464550 lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer. 2020 Jun 5 1
10 32581212 Enalapril overcomes chemoresistance and potentiates antitumor efficacy of 5-FU in colorectal cancer by suppressing proliferation, angiogenesis, and NF-κB/STAT3-regulated proteins. 2020 Jun 24 1
11 32606741 β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways. 2020 1
12 32755957 Chitosan nanoparticles loaded with aspirin and 5-fluororacil enable synergistic antitumour activity through the modulation of NF-κB/COX-2 signalling pathway. 2020 Aug 3
13 32879665 Interleukin-1 receptor antagonist enhances chemosensitivity to fluorouracil in treatment of Kras mutant colon cancer. 2020 Aug 15 2
14 32922964 The role of pharmacogenetics in keloid scar treatment: A literature review. 2020 Jan-Dec 1
15 30679569 5-Fluorouracil Induces Enteric Neuron Death and Glial Activation During Intestinal Mucositis via a S100B-RAGE-NFκB-Dependent Pathway. 2019 Jan 24 5
16 30741544 (-)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU by Inhibiting GRP78/NF-κB/miR-155-5p/MDR1 Pathway. 2019 Mar 6 2
17 31395078 Colorectal cancer cell-derived CCL20 recruits regulatory T cells to promote chemoresistance via FOXO1/CEBPB/NF-κB signaling. 2019 Aug 8 2
18 31729451 Aspirin suppresses chemoresistance and enhances antitumor activity of 5-Fu in 5-Fu-resistant colorectal cancer by abolishing 5-Fu-induced NF-κB activation. 2019 Nov 15 7
19 29467857 Overexpression of microRNA-15 increases the chemosensitivity of colon cancer cells to 5-fluorouracil and oxaliplatin by inhibiting the nuclear factor-κB signalling pathway and inducing apoptosis. 2018 Mar 1
20 29767264 Elemental diet inhibits pro‑inflammatory cytokine production in keratinocytes through the suppression of NF‑κB activation. 2018 Jul 2
21 28389232 An apple oligogalactan enhances the growth inhibitory effect of 5-fluorouracil on colorectal cancer. 2017 Jun 5 1
22 28531805 Troxerutin (TXN) potentiated 5-Fluorouracil (5-Fu) treatment of human gastric cancer through suppressing STAT3/NF-κB and Bcl-2 signaling pathways. 2017 Aug 5
23 29151957 Curcumin Enhances the Anticancer Effect Of 5-fluorouracil against Gastric Cancer through Down-Regulation of COX-2 and NF- κB Signaling Pathways. 2017 2
24 26522725 Inhibition of caspases primes colon cancer cells for 5-fluorouracil-induced TNF-α-dependent necroptosis driven by RIP1 kinase and NF-κB. 2016 Jun 30 1
25 26842876 Aspirin Suppresses the Acquisition of Chemoresistance in Breast Cancer by Disrupting an NFκB-IL6 Signaling Axis Responsible for the Generation of Cancer Stem Cells. 2016 Apr 1 1
26 27069140 NFκB-Associated Pathways in Progression of Chemoresistance to 5-Fluorouracil in an In Vitro Model of Colonic Carcinoma. 2016 Apr 2
27 27980427 Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway. 2016 4
28 25348361 DNA-PKcs deficiency sensitizes the human hepatoma HepG2 cells to cisplatin and 5-fluorouracil through suppression of the PI3K/Akt/NF-κB pathway. 2015 Jan 3
29 24435883 Icariin-mediated inhibition of NF-κB activity enhances the in vitro and in vivo antitumour effect of 5-fluorouracil in colorectal cancer. 2014 Jul 4
30 24452447 Overexpression of fibronectin confers cell adhesion-mediated drug resistance (CAM-DR) against 5-FU in oral squamous cell carcinoma cells. 2014 Apr 2
31 24587255 A compensatory role of NF-κB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines. 2014 6
32 24634414 Metallothionein 1G and zinc sensitize human colorectal cancer cells to chemotherapy. 2014 May 2
33 25134433 Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugs. 2014 Aug 18 2
34 23348635 Concurrent chemotherapy inhibits herpes simplex virus-1 replication and oncolysis. 2013 Feb 1
35 23451189 Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-κB and Src protein kinase signaling pathways. 2013 1
36 22292507 Immunohistochemical study of nuclear factor-κB expression in esophageal squamous cell carcinoma: prognostic significance and sensitivity to treatment with 5-FU. 2012 Nov-Dec 3
37 22412841 5-Fluorouracil induced intestinal mucositis via nuclear factor-κB activation by transcriptomic analysis and in vivo bioluminescence imaging. 2012 11
38 22825128 Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells. 2012 Oct 1
39 22905237 Molecular marker identification for relapse prediction in 5-FU-based adjuvant chemotherapy in gastric and colorectal cancers. 2012 2
40 23170132 Effect of NF-κB inhibitors on the chemotherapy-induced apoptosis of the colon cancer cell line HT-29. 2012 Oct 2
41 21196321 Sage components enhance cell death through nuclear factor kappa-B signaling. 2011 Jan 1 1
42 21617867 Inhibition of nuclear factor-κB activity by small interfering RNA in esophageal squamous cell carcinoma cell lines. 2011 Sep 4
43 19782464 Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines. 2010 Apr 1 1
44 19904749 The effect of focal adhesion kinase gene silencing on 5-fluorouracil chemosensitivity involves an Akt/NF-kappaB signaling pathway in colorectal carcinomas. 2010 Jul 1 1
45 20360934 Curcumin promotes apoptosis, increases chemosensitivity, and inhibits nuclear factor kappaB in esophageal adenocarcinoma. 2010 Apr 1
46 20433755 Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network. 2010 Apr 30 1
47 20570612 Wogonin potentiates the antitumor effects of low dose 5-fluorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism. 2010 Sep 1 1
48 19723887 Targeting NF-kappaB signaling pathway suppresses tumor growth, angiogenesis, and metastasis of human esophageal cancer. 2009 Sep 1
49 18075305 Synergistic effect of mTOR inhibitor rapamycin and fluorouracil in inducing apoptosis and cell senescence in hepatocarcinoma cells. 2008 Mar 2
50 17119966 Mechanisms of acquired chemoresistance to 5-fluorouracil and tomudex: thymidylate synthase dependent and independent networks. 2007 May 2