Dasatinib

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







407 Article(s)
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251 20222756 Dasatinib: is it all in the dose? 2010 Jun 2
252 20225261 The tyrosine kinase inhibitor dasatinib dysregulates bone remodeling through inhibition of osteoclasts in vivo. 2010 Aug 1
253 20305692 Bortezomib decreases Rb phosphorylation and induces caspase-dependent apoptosis in Imatinib-sensitive and -resistant Bcr-Abl1-expressing cells. 2010 Jun 3 1
254 20375898 Pleural effusions due to dasatinib. 2010 Jul 1
255 20406945 Dasatinib is preclinically active against Src-overexpressing human transitional cell carcinoma of the urothelium with activated Src signaling. 2010 May 1
256 20447687 A T315I mutation in e19a2 BCR/ABL1 chronic myeloid leukemia responding to dasatinib. 2010 Sep 1
257 20460883 Pre-emptive treatment with nilotinib after second allogeneic transplantation in a Philadelphia chromosome-positive acute lymphoblastic leukemia patient with high risk of relapse. 2010 1
258 20529808 Clinical algorithms for the treatment of patients with chronic myeloid leukemia: the 2010 perspective. 2010 Jun 1
259 20537386 BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: a review. 2010 Oct 2
260 20557276 Novel dual Src/Abl inhibitors for hematologic and solid malignancies. 2010 Aug 1
261 20585556 Role of Abl kinase and the Wave2 signaling complex in HIV-1 entry at a post-hemifusion step. 2010 Jun 17 1
262 20597967 Standard treatment of Ph+ CML in 2010: how, when and where not to use what BCR/ABL1 kinase inhibitor? 2010 Oct 1
263 20615173 Cost-effectiveness of dasatinib versus high-dose imatinib in patients with Chronic Myeloid Leukemia (CML), resistant to standard dose imatinib--a Swedish model application. 2010 Aug 1
264 20629079 Dasatinib induces autophagic cell death in human ovarian cancer. 2010 Nov 1 1
265 20860375 Photocleavable peptide-conjugated magnetic beads for protein kinase assays by MALDI-TOF MS. 2010 Oct 20 1
266 20875551 Chronic myeloid leukemia and second-generation tyrosine kinase inhibitors: when, how, and which one? 2010 Oct 1
267 20922699 [Cancer treatment-induced nephrotoxicity: BCR-Abl and VEGF inhibitors]. 2010 Sep-Oct 1
268 21108851 First-line treatment for chronic myeloid leukemia: dasatinib, nilotinib, or imatinib. 2010 Nov 26 2
269 18978822 Dasatinib-induced restoration of donor chimerism in BCR-ABL1-positive ALL after failure of imatinib therapy and allo-SCT. 2009 Apr 1
270 18984583 Crystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound state. 2009 Jan 2 1
271 19013641 Preclinical and clinical experience with dasatinib in Philadelphia chromosome-negative leukemias and myeloid disorders. 2009 May 1
272 19100678 Combined BCR-ABL inhibition with lentiviral-delivered shRNA and dasatinib augments induction of apoptosis in Philadelphia-positive cells. 2009 Feb 4
273 19190119 Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma. 2009 Feb 1
274 19195046 Dasatinib treatment for Philadelphia chromosome-positive leukemias: practical considerations. 2009 Apr 1 1
275 19236716 New dosing schedules of dasatinib for CML and adverse event management. 2009 Feb 23 1
276 19236722 The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2). 2009 Feb 24 1
277 19275507 New approved dasatinib regimen available for clinical use. 2009 Mar 1
278 19282395 Characterization of dasatinib and its structural analogs as CYP3A4 mechanism-based inactivators and the proposed bioactivation pathways. 2009 Jun 1
279 19295545 Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy. 2009 Aug 1
280 19296866 Protein kinase inhibitors: contributions from structure to clinical compounds. 2009 Feb 1
281 19363859 Hair depigmentation during chemotherapy with dasatinib, a dual Bcr-Abl/Src family tyrosine kinase inhibitor. 2009 Apr 2
282 19369231 Phase 3 study of dasatinib 140 mg once daily versus 70 mg twice daily in patients with chronic myeloid leukemia in accelerated phase resistant or intolerant to imatinib: 15-month median follow-up. 2009 Jun 18 2
283 19395585 Phase I study of the effect of gastric acid pH modulators on the bioavailability of oral dasatinib in healthy subjects. 2009 Jun 1
284 19402171 Dasatinib early intervention after cytogenetic or hematologic resistance to imatinib in patients with chronic myeloid leukemia. 2009 Jul 1 1
285 19455391 Clinical profile of dasatinib in Asian and non-Asian patients with chronic myeloid leukemia. 2009 Jun 1
286 19487385 Dasatinib in the treatment of chronic myeloid leukemia in accelerated phase after imatinib failure: the START a trial. 2009 Jul 20 1
287 19494352 The new tyrosine-kinase inhibitor and anticancer drug dasatinib reversibly affects platelet activation in vitro and in vivo. 2009 Aug 27 1
288 19502190 A once-daily dasatinib dosing strategy for chronic myeloid leukemia. 2009 Jun 1
289 19502192 Practical management of dasatinib for maximum patient benefit. 2009 Jun 1
290 19536317 Dasatinib in chronic myeloid leukemia: a review. 2009 Apr 1
291 19608684 A co-operative evaluation of different methods of detecting BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia on second-line dasatinib or nilotinib therapy after failure of imatinib. 2009 Sep 1
292 19641527 Dasatinib-associated major molecular responses in patients with chronic myeloid leukemia in chronic phase following imatinib failure: response dynamics and predictive value. 2009 Sep 1
293 19651622 Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics. 2009 Dec 1
294 19672773 Activation of the p38 Map kinase pathway is essential for the antileukemic effects of dasatinib. 2009 Dec 5
295 19706883 Acute dasatinib exposure commits Bcr-Abl-dependent cells to apoptosis. 2009 Oct 15 3
296 19779040 Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations. 2009 Dec 3 5
297 19793709 Treatment of chronic myeloid leukemia following imatinib resistance: a nursing guide to second-line treatment options. 2009 Oct 2
298 19794096 A novel dasatinib-sensitive RCSD1-ABL1 fusion transcript in chemotherapy-refractory adult pre-B lymphoblastic leukemia with t(1;9)(q24;q34). 2009 Oct 1
299 19844167 Systematically linking drug susceptibility to cancer genome aberrations. 2009 Nov 15 1
300 19878872 AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance. 2009 Nov 6 1