Title : First-line treatment for chronic myeloid leukemia: dasatinib, nilotinib, or imatinib.

Pub. Date : 2010 Nov 26

PMID : 21108851






2 Functional Relationships(s)
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1 Dasatinib and nilotinib, two newer drugs with higher potency than imatinib against BCR-ABL and activity against most imatinib-resistant BCR-ABL mutations, have each shown superior efficacy compared with imatinib for first-line treatment of chronic-phase CML in randomized phase 3 trials. Dasatinib ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 Dasatinib and nilotinib, two newer drugs with higher potency than imatinib against BCR-ABL and activity against most imatinib-resistant BCR-ABL mutations, have each shown superior efficacy compared with imatinib for first-line treatment of chronic-phase CML in randomized phase 3 trials. Dasatinib ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens