Title : [Metformin's effect on 5-fluorouracil,cisplatin,paclitaxel in laryngocarcinoma Hep-2 cells].

Pub. Date : 2017 Apr 5

PMID : 29871302






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The combination of metformin and 5-fluorouracil produced an antagonism action in Hep-2 cells.Western blot assay showed that metformin, cisplatin, 5-fluorouracil could have caused the increase of expression level of AMPK-alpha, P21 and Cyclin D1 in Hep-2 cells while Paclitaxel could have cause the decrease of expression level of Cyclin D1. Cisplatin cyclin dependent kinase inhibitor 1A Homo sapiens