Title : Long-term downregulation of Polo-like kinase 1 increases the cyclin-dependent kinase inhibitor p21(WAF1/CIP1).

Pub. Date : 2009 Feb 1

PMID : 19177004






1 Functional Relationships(s)
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1 Importantly, HeLa cells with reduced level of Plk1, which induces an increase of p21, p73 and Bax, are more sensitive to some chemotherapeutic agents, such as cisplatin. Cisplatin cyclin dependent kinase inhibitor 1A Homo sapiens