Title : The regulatory and predictive functions of miR-17 and miR-92 families on cisplatin resistance of non-small cell lung cancer.

Pub. Date : 2015 Oct 19

PMID : 26482648






2 Functional Relationships(s)
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1 RESULTS: The low expressions of miR-17 and miR-92 families can maintain cisplatin resistance through the regulation of CDKN1A and RAD21. Cisplatin cyclin dependent kinase inhibitor 1A Homo sapiens
2 As a result of high expressions of CDKN1A and RAD21, the inhibition of DNA synthesis and the repair of DNA damage are achieved and these may be two major contributing factors to cisplatin resistance. Cisplatin cyclin dependent kinase inhibitor 1A Homo sapiens