Genistein

cyclin dependent kinase inhibitor 1A ; Homo sapiens







31 Article(s)
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1 31438633 Induction of G2/M Cell Cycle Arrest and Apoptosis by Genistein in Human Bladder Cancer T24 Cells through Inhibition of the ROS-Dependent PI3k/Akt Signal Transduction Pathway. 2019 Aug 21 1
2 26003441 Effects of flavonoids on expression of genes involved in cell cycle regulation and DNA replication in human fibroblasts. 2015 Sep 1
3 25310747 Genistein decreases cellular redox potential, partially suppresses cell growth in HL‑60 leukemia cells and sensitizes cells to γ‑radiation‑induced cell death. 2014 Dec 1
4 23686257 Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells. 2013 Jul 1
5 21843532 Genistein, isoflavonoids in soybeans, prevents the formation of excess radiation-induced centrosomes via p21 up-regulation. 2011 Nov 1 3
6 19038232 Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4) Protein kinase modulation and reactive oxygen species generation. 2009 Feb 1 1
7 19263441 Molecular effects of soy phytoalexin glyceollins in human prostate cancer cells LNCaP. 2009 Sep 1
8 18324703 Puma is a novel target of soy isoflavone genistein but is dispensable for genistein-induced cell fate determination. 2008 Apr 1
9 18357397 The topoisomerase II inhibitor, genistein, induces G2/M arrest and apoptosis in human malignant glioma cell lines. 2008 Apr 1
10 18413741 Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification. 2008 Apr 15 4
11 16640785 Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest. 2006 Apr 26 2
12 14757171 Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1. 2004 Feb 15 3
13 15179686 [Enhancing effect of isoflavonoid genistein on radiosensitivity of DU145 prostate cancer cells]. 2004 May 1
14 12514295 Genistein activates p38 mitogen-activated protein kinase, inactivates ERK1/ERK2 and decreases Cdc25C expression in immortalized human mammary epithelial cells. 2003 Jan 2
15 12767922 P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells. 2003 Jun 13 22
16 11790449 Effect of flavonoids on cell cycle progression in prostate cancer cells. 2002 Feb 8 1
17 11170137 Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells. 2001 Feb 1 1
18 11286989 Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21(waf/cip1), p27(kip1), and Cdc25C expression. 2001 Apr 15 3
19 11295047 Synergistic effects of dexamethasone and genistein on the expression of Cdk inhibitor p21WAF1/CIP1 in human hepatocellular and colorectal carcinoma cells. 2001 May 5
20 11410520 Differential sensitivity of normal and malignant breast epithelial cells to genistein is partly mediated by p21(WAF1). 2001 Jun 11
21 11751518 Genistein elicits pleiotropic molecular effects on head and neck cancer cells. 2001 Dec 2
22 10761703 p53-independent induction of p21 (WAF1/CIP1), reduction of cyclin B1 and G2/M arrest by the isoflavone genistein in human prostate carcinoma cells. 2000 Feb 5
23 10912792 p21CIP1 is dispensable for the G2 arrest caused by genistein in human melanoma cells. 2000 Jul 10 1
24 11007941 Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents. 2000 Oct 15 2
25 11062152 Galectin-3 mediates genistein-induced G(2)/M arrest and inhibits apoptosis. 2000 Nov 9
26 11074606 Low-dose genistein induces cyclin-dependent kinase inhibitors and G(1) cell-cycle arrest in human prostate cancer cells. 2000 Oct 4
27 11776565 [Mechanism of growth inhibition by genistein of human breast carcinoma]. 1999 Sep 1
28 9513045 Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2/M arrest, and apoptosis. 1998 Apr 1 4
29 9664138 Genistein-induced G2/M arrest is associated with the inhibition of cyclin B1 and the induction of p21 in human breast carcinoma cells. 1998 Aug 2
30 9673352 Genistein inhibits both constitutive and EGF-stimulated invasion in ER-negative human breast carcinoma cell lines. 1998 May-Jun 1
31 9809990 Genistein exerts multiple suppressive effects on human breast carcinoma cells. 1998 Nov 1 2