Cisplatin

mutS homolog 2 ; Homo sapiens







36 Article(s)
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1 33640455 OTUB1 stabilizes mismatch repair protein MSH2 by blocking ubiquitination. 2021 Jan-Jun 1
2 33874956 CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer. 2021 Apr 19 5
3 32922493 A Preliminary Study of NER and MMR Pathways Involved in Chemotherapy Response in Bladder Transitional Cell Carcinoma: Impact on progression-free survival. 2020 Winter 1
4 30221354 Suppression of long noncoding RNA NCK1-AS1 increases chemosensitivity to cisplatin in cervical cancer. 2019 Apr 2
5 30414698 A Whole-genome CRISPR Screen Identifies a Role of MSH2 in Cisplatin-mediated Cell Death in Muscle-invasive Bladder Cancer. 2019 Feb 5
6 31666131 Hypermethylation of mismatch repair gene hMSH2 associates with platinum-resistant disease in epithelial ovarian cancer. 2019 Oct 30 3
7 27995412 HuCOP1 contributes to the regulation of DNA repair in keratinocytes. 2017 Mar 2
8 28536927 Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours. 2017 Aug 3
9 23420099 Factors affecting the sensitivity of human-derived esophageal carcinoma cell lines to 5-fluorouracil and cisplatin. 2013 Feb 1
10 23485110 Cisplatin upregulates MSH2 expression by reducing miR-21 to inhibit A549 cell growth. 2013 Mar 3
11 23724141 MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells. 2013 1
12 23761438 Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity. 2013 Aug 1
13 22269178 Cisplatin benefit is predicted by immunohistochemical analysis of DNA repair proteins in squamous cell carcinoma but not adenocarcinoma: theranostic modeling by NSCLC constituent histological subclasses. 2012 Sep 1
14 22737591 Molecular signaling mechanisms of apoptosis in hereditary non-polyposis colorectal cancer. 2012 Jun 15 1
15 21285347 MSH3 mediates sensitization of colorectal cancer cells to cisplatin, oxaliplatin, and a poly(ADP-ribose) polymerase inhibitor. 2011 Apr 8 1
16 21285353 hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis. 2011 Mar 25 1
17 20145178 MutS homologue 2 and the long-term benefit of adjuvant chemotherapy in lung cancer. 2010 Feb 15 1
18 23136600 Human MLH1 status can potentially predict cisplatin sensitivity but not microsatellite instability in head and neck squamous cell carcinoma cells. 2010 Jan 2
19 19484784 Synergistic effect of rapamycin and cisplatin in endometrial cancer cells. 2009 Sep 1 1
20 19175039 Analysis of hMLH1 and hMSH2 expression in cisplatin-treated ovarian cancer patients. 2008 Dec 2
21 17276589 Hsp27, Hsp70 and mismatch repair proteins hMLH1 and hMSH2 expression in peripheral blood lymphocytes from healthy subjects and cancer patients. 2007 Jul 8 1
22 16143448 DNA damage and repair in peripheral blood lymphocytes from healthy individuals and cancer patients: a pilot study on the implications in the clinical response to chemotherapy. 2006 Jul 28 2
23 16690105 Determination of the mechanism of gemcitabine modulation of cisplatin drug resistance in panel of human endometrial cancer cell lines. 2006 Nov 2
24 16716446 Mismatch repair system (MMR) status correlates with response and survival in non-small cell lung cancer (NSCLC) patients. 2006 Jul 1
25 14706347 Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells. 2004 Feb 3 2
26 12736115 Loss of hMLH1 expression correlates with improved survival in stage III-IV ovarian cancer patients. 2003 May 1
27 10048977 Expression of DNA repair proteins hMSH2, hMSH6, hMLH1, O6-methylguanine-DNA methyltransferase and N-methylpurine-DNA glycosylase in melanoma cells with acquired drug resistance. 1999 Mar 1 2
28 10360646 Loss of DNA mismatch repair facilitates reactivation of a reporter plasmid damaged by cisplatin. 1999 May 1
29 10408416 hMSH2 and GTBP expression in advanced stage epithelial ovarian cancer. 1999 Jul 1
30 9647613 Ongoing and unsaid on oxaliplatin: the hope. 1998 Jun 1
31 10397451 Expression of hMSH2 correlates with in vitro chemosensitivity to CDDP cytotoxicity in oral and oropharyngeal carcinoma. 1998 Oct 23 5
32 9157971 In vitro and in vivo resistance to cisplatin in cells that have lost DNA mismatch repair. 1997 May 15 1
33 9815561 Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells. 1997 Oct 1
34 21528244 Loss of DNA mismatch repair due to knockout of MSH2 or PMS2 results in resistance to cisplatin and carboplatin. 1997 Sep 2
35 8807890 The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatin. 1996 Jul 5
36 8895738 The role of DNA mismatch repair in platinum drug resistance. 1996 Nov 1 2