| 1 |
35336031 | Hepatoprotective Effect of Carob Pulp Flour (Ceratonia siliqua L.) Extract Obtained by Optimized Microwave-Assisted Extraction. | 2022 Mar 17 |
2 |
| 2 |
35369900 | Orientin reverses acetaminophen-induced acute liver failure by inhibiting oxidative stress and mitochondrial dysfunction. | 2022 May |
1 |
| 3 |
32571750 | Cytochrome P450 2E1 should not be neglected for acetaminophen-induced liver injury in metabolic diseases with altered insulin levels or glucose homeostasis. | 2021 Jan |
5 |
| 4 |
33759579 | The developing murine lung is susceptible to acetaminophen toxicity. | 2021 May 1 |
1 |
| 5 |
34233566 | Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress. | 2021 Jul 7 |
4 |
| 6 |
34585971 | Pulmonary implications of acetaminophen exposures independent of hepatic toxicity. | 2021 Nov 1 |
1 |
| 7 |
34770745 | Extract of Triticum aestivum Sprouts Suppresses Acetaminophen-Induced Hepatotoxicity in Mice by Inhibiting Oxidative Stress. | 2021 Oct 20 |
2 |
| 8 |
34907710 | Echinacoside alleviates acetaminophen-induced liver injury by attenuating oxidative stress and inflammatory cytokines in mice. | 2021 May |
1 |
| 9 |
31376085 | Effects of Photoperiod on Acetaminophen-Induced Hepatotoxicity in Mice. | 2020 Jan |
1 |
| 10 |
31768936 | The Effect of 4-Methylpyrazole on Oxidative Metabolism of Acetaminophen in Human Volunteers. | 2020 Apr |
1 |
| 11 |
31967706 | Irbesartan mitigates acute liver injury, oxidative stress, and apoptosis induced by acetaminophen in mice. | 2020 Dec |
1 |
| 12 |
32360799 | Oroxyloside ameliorates acetaminophen-induced hepatotoxicity by inhibiting JNK related apoptosis and necroptosis. | 2020 Aug 10 |
1 |
| 13 |
33157119 | 4-methylpyrazole protects against acetaminophen-induced acute kidney injury. | 2020 Dec 15 |
1 |
| 14 |
29735980 | Metabolic modulation of acetaminophen-induced hepatotoxicity by osteopontin. | 2019 May |
3 |
| 15 |
30706943 | Mannan-binding lectin attenuates acetaminophen-induced hepatotoxicity by regulating CYP2E1 expression via ROS-dependent JNK/SP1 pathway. | 2019 Apr |
1 |
| 16 |
30903181 | Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase. | 2019 Jul 1 |
1 |
| 17 |
30958500 | Allyl methyl trisulfide protected against acetaminophen (paracetamol)-induced hepatotoxicity by suppressing CYP2E1 and activating Nrf2 in mouse liver. | 2019 Apr 1 |
4 |
| 18 |
31600996 | Auriculatone Sulfate Effectively Protects Mice Against Acetaminophen-Induced Liver Injury. | 2019 Oct 9 |
1 |
| 19 |
31885815 | Toxic Acetaminophen Exposure Induces Distal Lung ER Stress, Proinflammatory Signaling, and Emphysematous Changes in the Adult Murine Lung. | 2019 |
3 |
| 20 |
32257904 | Comparison of toxic responses to acetaminophen challenge in ICR mice originating from different sources. | 2019 |
1 |
| 21 |
29940935 | Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice. | 2018 Jun 25 |
2 |
| 22 |
30030101 | Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro. | 2018 Oct |
1 |
| 23 |
30039229 | Spatio-temporal visualization of the distribution of acetaminophen as well as its metabolites and adducts in mouse livers by MALDI MSI. | 2018 Sep |
1 |
| 24 |
28205631 | Immature mice are more susceptible than adult mice to acetaminophen-induced acute liver injury. | 2017 Feb 16 |
1 |
| 25 |
28668488 | Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice. | 2017 Sep |
2 |
| 26 |
28832650 | Fructose diet alleviates acetaminophen-induced hepatotoxicity in mice. | 2017 |
2 |
| 27 |
28963035 | miRNA-122 Protects Mice and Human Hepatocytes from Acetaminophen Toxicity by Regulating Cytochrome P450 Family 1 Subfamily A Member 2 and Family 2 Subfamily E Member 1 Expression. | 2017 Dec |
2 |
| 28 |
29056914 | Acetaminophen-Induced Liver Injury Alters the Acyl Ethanolamine-Based Anti-Inflammatory Signaling System in Liver. | 2017 |
1 |
| 29 |
29184146 | 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2. | 2017 Nov 28 |
2 |
| 30 |
28066249 | Development of an IgY Antibody-Based Immunoassay for the Screening of the CYP2E1 Inhibitor/Enhancer from Herbal Medicines. | 2016 |
1 |
| 31 |
25319358 | Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration. | 2015 Jan |
1 |
| 32 |
25753323 | Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation. | 2015 Apr 25 |
2 |
| 33 |
25884831 | Aminotriazole alleviates acetaminophen poisoning via downregulating P450 2E1 and suppressing inflammation. | 2015 |
3 |
| 34 |
25914167 | IL-6 trans-signaling plays important protective roles in acute liver injury induced by acetaminophen in mice. | 2015 Jun |
1 |
| 35 |
23150232 | Increased susceptibility of natural killer T-cell-deficient mice to acetaminophen-induced liver injury. | 2013 Apr |
2 |
| 36 |
23935693 | Curative Effects of Thiacremonone against Acetaminophen-Induced Acute Hepatic Failure via Inhibition of Proinflammatory Cytokines Production and Infiltration of Cytotoxic Immune Cells and Kupffer Cells. | 2013 |
3 |
| 37 |
22291093 | IRE1α activation protects mice against acetaminophen-induced hepatotoxicity. | 2012 Feb 13 |
3 |
| 38 |
23272189 | Melatonin protects against apoptosis-inducing factor (AIF)-dependent cell death during acetaminophen-induced acute liver failure. | 2012 |
3 |
| 39 |
19660437 | Role of cytochrome P450 2E1 in protein nitration and ubiquitin-mediated degradation during acetaminophen toxicity. | 2010 Jan 1 |
5 |
| 40 |
20067817 | Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation. | 2010 Feb 28 |
1 |
| 41 |
19256530 | Serum metabolomics reveals irreversible inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity. | 2009 Apr |
5 |
| 42 |
19459732 | Hepatoprotective effects of an anthocyanin fraction from purple-fleshed sweet potato against acetaminophen-induced liver damage in mice. | 2009 Apr |
2 |
| 43 |
19799668 | Protective effects from carnosine and histidine on acetaminophen-induced liver injury. | 2009 Oct |
1 |
| 44 |
18093979 | Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and Cyp2e1-null mice. | 2008 Feb 22 |
4 |
| 45 |
18583171 | Role of CYP2E1 in the mouse model of MPTP toxicity. | 2008 |
1 |
| 46 |
17392391 | Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice. | 2007 Jul |
3 |
| 47 |
17979661 | Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using Cyp2e1(-/-) mice. | 2007 Oct |
2 |
| 48 |
16393943 | Dietary steatotic liver attenuates acetaminophen hepatotoxicity in mice. | 2006 Jan |
2 |
| 49 |
16948781 | Mechanisms of protection by melatonin against acetaminophen-induced liver injury in mice. | 2006 Oct |
2 |
| 50 |
15576447 | The cyp2e1-humanized transgenic mouse: role of cyp2e1 in acetaminophen hepatotoxicity. | 2005 Mar |
5 |