Pub. Date : 2021 Jul 7
PMID : 34233566
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this context, CYP2E1 converts paracetamol (PCM) to N-acetyl-p-benzoquinone imine (NAPQI), which is prone to cause hepatotoxicity. | Acetaminophen | cytochrome P450, family 2, subfamily e, polypeptide 1 | Mus musculus |
| 2 | In this context, CYP2E1 converts paracetamol (PCM) to N-acetyl-p-benzoquinone imine (NAPQI), which is prone to cause hepatotoxicity. | Acetaminophen | cytochrome P450, family 2, subfamily e, polypeptide 1 | Mus musculus |
| 3 | Significant down-regulation of CYP2E1 protein and its mRNA expression levels were observed in the glabridin-treated groups compared to PCM-induced respective elevation of CYP2E1. | Acetaminophen | cytochrome P450, family 2, subfamily e, polypeptide 1 | Mus musculus |
| 4 | Significant down-regulation of CYP2E1 protein and its mRNA expression levels were observed in the glabridin-treated groups compared to PCM-induced respective elevation of CYP2E1. | Acetaminophen | cytochrome P450, family 2, subfamily e, polypeptide 1 | Mus musculus |