2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

cyclin dependent kinase inhibitor 1B ; Homo sapiens







21 Article(s)
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1 25821107 PI3K/AKT pathway-mediated regulation of p27(Kip1) is associated with cell cycle arrest and apoptosis in cervical cancer. 2015 Jun 2
2 24574749 Epidermal growth factor upregulates Skp2/Cks1 and p27(kip1) in human extrahepatic cholangiocarcinoma cells. 2014 Jan 21 1
3 22552808 A novel function of FoxO transcription factors in thrombin-stimulated vascular smooth muscle cell proliferation. 2012 Jul 1
4 21477582 UBE2M-mediated p27(Kip1) degradation in gemcitabine cytotoxicity. 2011 Jul 1 1
5 20661471 Co-depletion of cathepsin B and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27 upregulation. 2010 Jul 22 2
6 20736003 Inhibition of phosphatidylinositol 3-kinase promotes tumor cell resistance to chemotherapeutic agents via a mechanism involving delay in cell cycle progression. 2010 Nov 15 1
7 21042767 Inhibition of activated phosphatidylinositol 3-kinase/AKT pathway in malignant pleural mesothelioma leads to G1 cell cycle arrest. 2010 Dec 1
8 19443725 Dependence of EGF-induced increases in corneal epithelial proliferation and migration on GSK-3 inactivation. 2009 Oct 1
9 19533041 Iron-saturated lactoferrin stimulates cell cycle progression through PI3K/Akt pathway. 2009 Jul 31 1
10 17407140 Overexpression of integrin beta1 inhibits proliferation of hepatocellular carcinoma cell SMMC-7721 through preventing Skp2-dependent degradation of p27 via PI3K pathway. 2007 Oct 15 2
11 16479173 AKT pathway is activated by 1, 25-dihydroxyvitamin D3 and participates in its anti-apoptotic effect and cell cycle control in differentiating HL60 cells. 2006 Feb 1
12 16790529 Connective tissue growth factor/CCN2 stimulates actin disassembly through Akt/protein kinase B-mediated phosphorylation and cytoplasmic translocation of p27(Kip-1). 2006 Aug 1
13 14605879 Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45. 2004 Jan 1
14 15084985 Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines. 2004 Apr 1
15 12835226 Mechanosensitive p27Kip1 regulation and cell cycle entry in vascular smooth muscle cells. 2003 Aug 5 1
16 11850846 Phosphatidylinositol 3-kinase is essential for the proliferation of lymphoblastoid cells. 2002 Feb 14 1
17 12242656 Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma. 2002 Sep 26 1
18 11709727 ErbB2-overexpressing human mammary carcinoma cells display an increased requirement for the phosphatidylinositol 3-kinase signaling pathway in anchorage-independent growth. 2001 Nov 8 1
19 11010972 BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway. 2000 Dec 15 1
20 9498822 G1 phase arrest by the phosphatidylinositol 3-kinase inhibitor LY 294002 is correlated to up-regulation of p27Kip1 and inhibition of G1 CDKs in choroidal melanoma cells. 1998 Feb 6 1
21 9860981 PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells. 1998 Dec 22 1