Title : Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.

Pub. Date : 2002 Sep 26

PMID : 12242656






1 Functional Relationships(s)
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1 In the presence of LY294002, cell-cycle arrest in G0/G1 was observed, p27(Kip1) protein expression was up-regulated whereas the expression of both Skp2 and cyclin D1 dramatically diminished. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one cyclin dependent kinase inhibitor 1B Homo sapiens