| 1 |
30742098 | Targeting SYK signaling in myeloid cells protects against liver fibrosis and hepatocarcinogenesis. | 2019 Jun |
1 |
| 2 |
29104084 | Orthopaedic implant materials drive M1 macrophage polarization in a spleen tyrosine kinase- and mitogen-activated protein kinase-dependent manner. | 2018 Jan |
1 |
| 3 |
29137913 | Neutrophil CD16b crosslinking induces lipid raft-mediated activation of SHP-2 and affects cytokine expression and retarded neutrophil apoptosis. | 2018 Jan 1 |
3 |
| 4 |
29231998 | Phosphorylated Tyr142 β-catenin localizes to centrosomes and is regulated by Syk. | 2018 Apr |
2 |
| 5 |
29137391 | Activated spleen tyrosine kinase promotes malignant progression of oral squamous cell carcinoma via mTOR/S6 signaling pathway in an ERK1/2-independent manner. | 2017 Oct 13 |
1 |
| 6 |
26277637 | Nanoparticles enhance the ability of human neutrophils to exert phagocytosis by a Syk-dependent mechanism. | 2015 Nov |
2 |
| 7 |
24326074 | A critical role for the regulation of Syk from agglutination to aggregation in human platelets. | 2014 Jan 10 |
1 |
| 8 |
23263853 | Viscum album agglutinin-I (VAA-I) increases cell surface expression of cytoskeletal proteins in apoptotic human neutrophils: moesin and ezrin are two novel targets of VAA-I. | 2013 Oct |
1 |
| 9 |
23713607 | Piceatannol modulates lung epithelial cellular responses to Pseudomonas aeruginosa. | 2013 Oct |
5 |
| 10 |
23726836 | Tetramethylpyrazine attenuates TNF-α-induced iNOS expression in human endothelial cells: Involvement of Syk-mediated activation of PI3K-IKK-IκB signaling pathways. | 2013 Aug 15 |
2 |
| 11 |
22108298 | Biological activity of piceatannol: leaving the shadow of resveratrol. | 2012 Jan-Mar |
1 |
| 12 |
20951127 | Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways. | 2011 Jan 10 |
1 |
| 13 |
21325831 | Regulation of serotonin transport in human platelets by tyrosine kinase Syk. | 2011 |
2 |
| 14 |
21394647 | Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling. | 2011 Apr |
1 |
| 15 |
21642504 | Angiotensin II-induced process of angiogenesis is mediated by spleen tyrosine kinase via VEGF receptor-1 phosphorylation. | 2011 Sep |
2 |
| 16 |
19797620 | Angiotensin II-induced migration of vascular smooth muscle cells is mediated by p38 mitogen-activated protein kinase-activated c-Src through spleen tyrosine kinase and epidermal growth factor receptor transactivation. | 2010 Jan |
3 |
| 17 |
19925860 | Syk is a novel target of arsenic trioxide (ATO) and is involved in the toxic effect of ATO in human neutrophils. | 2010 Apr |
2 |
| 18 |
20089415 | Poly(I:C) induces BLyS-expression of airway fibroblasts through phosphatidylinositol 3-kinase. | 2010 May |
1 |
| 19 |
19638624 | A fundamental role of mAbp1 in neutrophils: impact on beta(2) integrin-mediated phagocytosis and adhesion in vivo. | 2009 Nov 5 |
1 |
| 20 |
19783684 | IL-4R(alpha), a new member that associates with Syk kinase: implication in IL-4-induced human neutrophil functions. | 2009 Oct 15 |
4 |
| 21 |
18207024 | Role of different protein tyrosine kinases in fMLP-induced neutrophil transmigration. | 2008 |
1 |
| 22 |
18390758 | Costimulation of dectin-1 and DC-SIGN triggers the arachidonic acid cascade in human monocyte-derived dendritic cells. | 2008 Apr 15 |
1 |
| 23 |
18715989 | Platelets undergo phosphorylation of Syk at Y525/526 and Y352 in response to pathophysiological shear stress. | 2008 Oct |
1 |
| 24 |
17063483 | A role for PLCgamma2 in platelet activation by homocysteine. | 2007 Apr 1 |
1 |
| 25 |
17095576 | C-reactive protein suppresses insulin signaling in endothelial cells: role of spleen tyrosine kinase. | 2007 Feb |
1 |
| 26 |
17228323 | Tyrosine kinase Syk associates with toll-like receptor 4 and regulates signaling in human monocytic cells. | 2007 Apr-May |
2 |
| 27 |
18025182 | NKp30 ligation induces rapid activation of the canonical NF-kappaB pathway in NK cells. | 2007 Dec 1 |
1 |
| 28 |
16603696 | CRP promotes monocyte-endothelial cell adhesion via Fcgamma receptors in human aortic endothelial cells under static and shear flow conditions. | 2006 Sep |
1 |
| 29 |
16902949 | Differing mechanisms of cAMP- versus seawater-induced oocyte maturation in marine nemertean worms II. The roles of tyrosine kinases and phosphatases. | 2006 Dec |
1 |
| 30 |
16912221 | Syk-dependent mTOR activation in follicular lymphoma cells. | 2006 Dec 15 |
1 |
| 31 |
15455373 | Reactivation of SYK expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness. | 2005 Feb 10 |
2 |
| 32 |
15557085 | Syk tyrosine kinase participates in beta1-integrin signaling and inflammatory responses in airway epithelial cells. | 2005 Mar |
2 |
| 33 |
15795233 | Thrombin-induced tyrosine phosphorylation of HS1 in human platelets is sequentially catalyzed by Syk and Lyn tyrosine kinases and associated with the cellular migration of the protein. | 2005 Jun 3 |
1 |
| 34 |
16148119 | Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (Fractalkine). | 2005 Sep 15 |
1 |
| 35 |
16289055 | Engagement of PSGL-1 upregulates CSF-1 transcription via a mechanism that may involve Syk. | 2005 Sep |
1 |
| 36 |
16389569 | C-reactive protein mediates CD11b expression in monocytes through the non-receptor tyrosine kinase, Syk, and calcium mobilization but not through cytosolic peroxides. | 2005 Dec |
2 |
| 37 |
14691575 | A role for p38 MAP kinase in platelet activation by von Willebrand factor. | 2004 Jan |
1 |
| 38 |
14699155 | Lipopolysaccharide-induced c-Jun NH2-terminal kinase activation in human neutrophils: role of phosphatidylinositol 3-Kinase and Syk-mediated pathways. | 2004 Mar 19 |
1 |
| 39 |
14978183 | Activation of Syk in neutrophils by antineutrophil cytoplasm antibodies occurs via Fcgamma receptors and CD18. | 2004 Mar |
2 |
| 40 |
14982949 | Fcgamma receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction. | 2004 Jun |
2 |
| 41 |
15050291 | Tyrosine phosphorylation-dependent activation of NFkappaB is compromised in T cells from the elderly. | 2004 Apr |
1 |
| 42 |
15123770 | Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain. | 2004 Jul |
2 |
| 43 |
15163542 | An IgM class anti-neutrophil cytoplasm antibody inhibits neutrophil adhesion and apoptosis via a Syk dependent signaling cascade. | 2004 Jun |
1 |
| 44 |
15240695 | TNF activates Syk protein tyrosine kinase leading to TNF-induced MAPK activation, NF-kappaB activation, and apoptosis. | 2004 Jul 15 |
2 |
| 45 |
12393431 | Regulation of Akt-dependent cell survival by Syk and Rac. | 2003 Jan 1 |
2 |
| 46 |
12435267 | Fgr but not Syk tyrosine kinase is a target for beta 2 integrin-induced c-Cbl-mediated ubiquitination in adherent human neutrophils. | 2003 Mar 1 |
8 |
| 47 |
12477728 | Syk, a protein-tyrosine kinase, suppresses the cell motility and nuclear factor kappa B-mediated secretion of urokinase type plasminogen activator by inhibiting the phosphatidylinositol 3'-kinase activity in breast cancer cells. | 2003 Feb 21 |
2 |
| 48 |
12606772 | Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation. | 2003 Mar |
1 |
| 49 |
12885943 | A role for Syk-kinase in the control of the binding cycle of the beta2 integrins (CD11/CD18) in human polymorphonuclear neutrophils. | 2003 Aug |
1 |
| 50 |
14638865 | Possible role of cell surface H+ -ATP synthase in the extracellular ATP synthesis and proliferation of human umbilical vein endothelial cells. | 2003 Nov |
1 |