Title : Nanoparticles enhance the ability of human neutrophils to exert phagocytosis by a Syk-dependent mechanism.

Pub. Date : 2015 Nov

PMID : 26277637






2 Functional Relationships(s)
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1 Syk activation was assessed by western blot experiments and a pharmacological approach with piceatannol, a Syk inhibitor, was used to determine its role in NPs-induced neutrophils. 3,3',4,5'-tetrahydroxystilbene spleen associated tyrosine kinase Homo sapiens
2 Syk was activated in NPs-induced neutrophils as evidenced by its increased tyrosine phosphorylation level vs controls and the ability of NPs-induced phagocytosis was reversed by piceatannol. 3,3',4,5'-tetrahydroxystilbene spleen associated tyrosine kinase Homo sapiens