Tadalafil

phosphodiesterase 5A ; Homo sapiens







301 Article(s)
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101 23613014 Decreased permeability surface area for glucose in obese women with postprandial hyperglycemia: no effect of phosphodiesterase-5 (PDE-5) inhibition. 2013 Aug 2
102 23656343 Phosphodiesterase inhibitors in clinical urology. 2013 May 1
103 23765639 PDE5 inhibitors blunt inflammation in human BPH: a potential mechanism of action for PDE5 inhibitors in LUTS. 2013 Sep 1
104 23804703 Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. 2013 Sep 3
105 23876588 Efficacy and safety of tadalafil 5 mg once daily for lower urinary tract symptoms suggestive of benign prostatic hyperplasia: subgroup analyses of pooled data from 4 multinational, randomized, placebo-controlled clinical studies. 2013 Sep 2
106 23917809 Effectiveness and safety of phosphodiesterase 5 inhibitors in patients with cardiovascular disease and hypertension. 2013 Oct 1
107 23949822 Tadalafil for benign prostatic hyperplasia. 2013 Aug 2
108 24180640 The molecular basis for the selectivity of tadalafil toward phosphodiesterase 5 and 6: a modeling study. 2013 Nov 25 10
109 24419925 [Use of 5-phosphodiesterase inhibitors in patients with LUTS secondary to BPH: our experience and review of the literature]. 2013 Sep-Dec 1
110 24432631 [Cardiovascular-protective effect of tadalafil in the treatment of erectile dysfunction]. 2013 Dec 2
111 26558086 Phosphodiesterase type 5 inhibitors as a treatment for erectile dysfunction: Current information and new horizons. 2013 Sep 1
112 22156704 Should central serous chorioretinopathy be added to the list of ocular side effects of phosphodiesterase 5 inhibitors? 2012 2
113 22304626 Treating erectile dysfunction and central neurological diseases with oral phosphodiesterase type 5 inhibitors. Review of the literature. 2012 Apr 1
114 22377518 Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 2. Tadalafil analogs. 2012 Apr 1 1
115 22707162 Identification of phototransformation products of sildenafil (Viagra) and its N-demethylated human metabolite under simulated sunlight. 2012 Jun 2
116 22725705 Chronic PDE-5 inhibition in patients with erectile dysfunction - a treatment approach using tadalafil once-daily. 2012 Jul 4
117 22759598 Tadalafil enhances the inhibitory effects of tamsulosin on neurogenic contractions of human prostate and bladder neck. 2012 Sep 1
118 22947364 The pleiotropic effects of phosphodiesterase 5 inhibitors on function and safety in patients with cardiovascular disease and hypertension. 2012 Sep 1
119 23033484 Identification of amino acid residues responsible for the selectivity of tadalafil binding to two closely related phosphodiesterases, PDE5 and PDE6. 2012 Nov 30 3
120 23117589 Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel β-carboline derivatives. 2012 Nov 1
121 23297507 [Tadalafil rehabilitation therapy for erectile dysfunction following prostatectomy]. 2012 Oct 1
122 24779692 Determination of PDE-5 inhibitors and appetite suppressants in adulterated dietary supplements using LC/PDA and LC/MS. 2012 1
123 26676704 Phosphodiesterase Type 5 Inhibitor and Erectile Dysfunction in Lower Urinary Tract Symptoms. 2012 Mar 2
124 20704642 Hypogonadal men nonresponders to the PDE5 inhibitor tadalafil benefit from normalization of testosterone levels with a 1% hydroalcoholic testosterone gel in the treatment of erectile dysfunction (TADTEST study). 2011 Jan 1
125 20859794 Inhibition of cyclic nucleotide phosphodiesterases by methylxanthines and related compounds. 2011 2
126 21054754 Activity of phosphodiesterase type 5 inhibitors in patients with lower urinary tract symptoms due to benign prostatic hyperplasia. 2011 Jun 1
127 21194760 Brachial artery flow mediated assessment: a tool to predict the response to chronic PDE5 inhibition with tadalafil in patients with erectile dysfunction. 2011 Feb 3 1
128 21275598 Leber's hereditary optic neuropathy precipitated by tadalafil use for erectile dysfunction. 2011 Jan 2
129 21284024 Tadalafil for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia: pathophysiology and mechanism(s) of action. 2011 Mar 1
130 21384413 Design, synthesis and structure-activity relationship of functionalized tetrahydro-β-carboline derivatives as novel PDE5 inhibitors. 2011 Mar 2
131 21460862 Prevalence and medical management of erectile dysfunction in Asia. 2011 Jul 1
132 21504142 Drug to genome to drug: discovery of new antiplasmodial compounds. 2011 May 12 1
133 21585174 The management of erectile dysfunction: innovations and future perspectives. 2011 Mar 1
134 21620965 Conformational conversion of PDE5 by incubation with sildenafil or metal ion is accompanied by stimulation of allosteric cGMP binding. 2011 Oct 2
135 21702653 Tadalafil for the treatment of pulmonary arterial hypertension. 2011 Jun 2
136 21707928 A randomized, double-blind, placebo-controlled, parallel study to assess the efficacy and safety of once-a-day tadalafil in men with erectile dysfunction who are naïve to PDE5 inhibitors. 2011 Sep 2
137 21719226 Development and validation of a GC/MS method for the determination of tadalafil in whole blood. 2011 Nov 1 2
138 21762988 Tadalafil: a long-acting phosphodiesterase-5 inhibitor for the treatment of pulmonary arterial hypertension. 2011 Aug 5
139 21768131 Identify drug repurposing candidates by mining the protein data bank. 2011 Jul 1
140 21771280 Are phosphodiesterase type 5 inhibitors associated with vision-threatening adverse events? A critical analysis and review of the literature. 2011 Oct 1
141 21812935 Phosphodiesterase type 5 expression in human and rat lower urinary tract tissues and the effect of tadalafil on prostate gland oxygenation in spontaneously hypertensive rats. 2011 Oct 1
142 21914136 Clinical efficacy of phosphodiesterase-5 inhibitor tadalafil in Eisenmenger syndrome--a randomized, placebo-controlled, double-blind crossover study. 2011 Sep-Oct 3
143 21961252 [Psychosomatic treatment: a key to the improvement of erectile dysfunction]. 2011 Sep 2
144 21995676 Phosphodiesterase type 5 (PDE5) inhibitors in erectile dysfunction: the proper drug for the proper patient. 2011 Dec 1
145 22131856 Emerging new uses of phosphodiesterase-5 inhibitors in cardiovascular diseases. 2011 Winter 1
146 22469265 Tadalafil. 2011 1
147 23351473 [Tadalafil: novel aspects of phosphodiesterase-5 inhibition in the treatment of pulmonary hypertension]. 2011 2
148 19171388 Combination of sitaxentan and tadalafil for idiopathic pulmonary arterial hypertension following relapse on bosentan. 2010 Oct 29 1
149 19185976 Effects of phosphodiesterase inhibitors on the inflammatory response of endothelial cells stimulated by myeloperoxidase-modified low-density lipoprotein or tumor necrosis factor alpha. 2010 Mar 2
150 19428174 Combination of alfuzosin and tadalafil exerts an additive relaxant effect on human detrusor and prostatic tissues in vitro. 2010 Apr 2