Title : Tadalafil enhances the inhibitory effects of tamsulosin on neurogenic contractions of human prostate and bladder neck.

Pub. Date : 2012 Sep

PMID : 22759598






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1 AIM: To determine the effects of the long-acting PDE5 inhibitor, tadalafil, on smooth muscle tone in human prostate and bladder neck as well as to evaluate the influence of tadalafil on the efficacy of the alpha-adrenergic receptor antagonist, tamsulosin, in inhibiting contractile responses in these tissues. Tadalafil phosphodiesterase 5A Homo sapiens