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33007330 | FGFR1 overexpression renders breast cancer cells resistant to metformin through activation of IRS1/ERK signaling. | 2021 Jan |
3 |
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33058005 | TSH lowering effects of metformin: a possible mechanism of action. | 2021 Jul |
1 |
| 3 |
33927970 | Role of insulin receptor substance-1 modulating PI3K/Akt insulin signaling pathway in Alzheimer's disease. | 2021 Apr |
1 |
| 4 |
31205529 | Metformin Induces Apoptosis and Inhibits Proliferation through the AMP-Activated Protein Kinase and Insulin-like Growth Factor 1 Receptor Pathways in the Bile Duct Cancer Cells. | 2019 |
6 |
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30259865 | Bifurcation analysis of insulin regulated mTOR signalling pathway in cancer cells. | 2018 Oct |
3 |
| 6 |
30410867 | Erratum to: Metformin treatment ameliorates diabetes-associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1. | 2018 Nov |
1 |
| 7 |
25891779 | Metformin attenuates palmitic acid-induced insulin resistance in L6 cells through the AMP-activated protein kinase/sterol regulatory element-binding protein-1c pathway. | 2015 Jun |
5 |
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24903160 | Metformin prevents LYRM1-induced insulin resistance in 3T3-L1 adipocytes via a mitochondrial-dependent mechanism. | 2014 Dec |
1 |
| 9 |
23663483 | Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells. | 2013 May 10 |
1 |
| 10 |
22968630 | NYGGF4 (PID1) effects on insulin resistance are reversed by metformin in 3T3-L1 adipocytes. | 2012 Dec |
2 |
| 11 |
23133528 | The hepatitis C virus modulates insulin signaling pathway in vitro promoting insulin resistance. | 2012 |
1 |
| 12 |
23141431 | Metformin enhances the action of insulin on porcine granulosa-lutein cells in vitro. | 2012 Dec |
1 |
| 13 |
21209036 | Action of metformin on the insulin-signaling pathway and on glucose transport in human granulosa cells. | 2011 Mar |
1 |
| 14 |
20038265 | Metformin regulates palmitate-induced apoptosis and ER stress response in HepG2 liver cells. | 2010 Jun |
1 |
| 15 |
20135346 | Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells. | 2010 Aug |
1 |
| 16 |
20363874 | AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation. | 2010 Jun |
2 |
| 17 |
20977583 | Genetic variants of the insulin receptor substrate-1 are influencing the therapeutic efficacy of oral antidiabetics. | 2010 Dec |
2 |
| 18 |
18972094 | Combined thiazolidinedione-metformin treatment synergistically improves insulin signalling to insulin receptor substrate-1-dependent phosphatidylinositol 3-kinase, atypical protein kinase C and protein kinase B/Akt in human diabetic muscle. | 2009 Jan |
3 |
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19418728 | [Effect of the Gly972Arg, SNP43 and Prol2Ala polymorphisms of the genes IRS1, CAPN10 and PPARG2 on secondary failure to sulphonylurea and metformin in patients with type 2 diabetes in Yucatán, México]. | 2009 Mar |
2 |
| 20 |
17698034 | Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes. | 2007 Oct 12 |
1 |
| 21 |
16354680 | Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation. | 2006 Jan |
1 |
| 22 |
15665022 | The importance of IRS-1 Gly972Arg polymorphism in evaluating the response to metformin treatment in polycystic ovary syndrome. | 2005 May |
3 |
| 23 |
14761669 | Combination of metformin and thiazolidindiones restore insulin signalling in insulin-resistant cultured myotubes. | 2004 Feb 27 |
4 |
| 24 |
12511230 | Metformin modulates insulin post-receptor signaling transduction in chronically insulin-treated Hep G2 cells. | 2003 Jan |
2 |
| 25 |
12629126 | Metformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2. | 2003 Mar |
1 |
| 26 |
12237252 | Metformin enhances insulin signalling in insulin-dependent and-independent pathways in insulin resistant muscle cells. | 2002 Oct |
1 |