664 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
601 | 24270740 | BTK inhibition targets in vivo CLL proliferation through its effects on B-cell receptor signaling activity. | 2014 Mar | 3 |
602 | 24307721 | Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia. | 2014 Feb 20 | 4 |
603 | 24311722 | Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL). | 2014 Feb 20 | 2 |
604 | 24332241 | Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: an open-label, multicentre, phase 1b/2 trial. | 2014 Jan | 1 |
605 | 24338680 | The promising impact of ibrutinib, a Bruton's tyrosine kinase inhibitor, for the management of lymphoid malignancies. | 2014 Mar | 3 |
606 | 24357428 | Bruton's tyrosine kinase (BTK) inhibitors in clinical trials. | 2014 Mar | 3 |
607 | 24415539 | Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy. | 2014 Mar 20 | 2 |
608 | 24445187 | Ibrutinib and indolent B-cell lymphomas. | 2014 Aug | 2 |
609 | 24472371 | Ibrutinib for B cell malignancies. | 2014 Jan 28 | 4 |
610 | 24481980 | Ibrutinib in B-cell Lymphomas. | 2014 Jun | 2 |
611 | 24598688 | [Ibrutinib in the treatment of chronic lymphocytic leukemia and other B-cell malignancies]. | 2014 Feb | 1 |
612 | 24612681 | Bruton tyrosine kinase mediates TLR9-dependent human dendritic cell activation. | 2014 Jun | 2 |
613 | 24659631 | Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL. | 2014 May 22 | 1 |
614 | 24693884 | Different sensitivity of germinal center B cell-like diffuse large B cell lymphoma cells towards ibrutinib treatment. | 2014 Apr 3 | 2 |
615 | 24697238 | The bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) blocks hairy cell leukaemia survival, proliferation and B cell receptor signalling: a new therapeutic approach. | 2014 Jul | 4 |
616 | 24756799 | Ibrutinib. | 2014 | 1 |
617 | 24759210 | Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor. | 2014 Apr 24 | 1 |
618 | 24778403 | Bruton's tyrosine kinase: from X-linked agammaglobulinemia toward targeted therapy for B-cell malignancies. | 2014 Jun 10 | 1 |
619 | 24829205 | Kinetics of CLL cells in tissues and blood during therapy with the BTK inhibitor ibrutinib. | 2014 Jun 26 | 3 |
620 | 24869598 | Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib. | 2014 Jun 12 | 8 |
621 | 24895895 | Bruton's TK inhibitors: structural insights and evolution of clinical candidates. | 2014 Apr | 1 |
622 | 24918646 | Ibrutinib for the treatment of chronic lymphocytic leukemia and mantle cell lymphoma. | 2014 Apr | 3 |
623 | 24957109 | Characterization of ibrutinib-sensitive and -resistant mantle lymphoma cells. | 2014 Sep | 6 |
624 | 24970801 | Synergistic induction of apoptosis by combination of BTK and dual mTORC1/2 inhibitors in diffuse large B cell lymphoma. | 2014 Jul 15 | 1 |
625 | 25026208 | Ibrutinib treatment of CLL: the cancer fights back. | 2014 Jul 14 | 2 |
626 | 25042202 | Combination of ibrutinib with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) for treatment-naive patients with CD20-positive B-cell non-Hodgkin lymphoma: a non-randomised, phase 1b study. | 2014 Aug | 1 |
627 | 25081321 | Ibrutinib (ImbruvicaTM) potently inhibits ErbB receptor phosphorylation and cell viability of ErbB2-positive breast cancer cells. | 2014 Dec | 1 |
628 | 25082755 | Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma. | 2014 Sep | 9 |
629 | 25150798 | Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study. | 2014 Sep | 2 |
630 | 25158606 | Ibrutinib for the treatment of mantle cell lymphoma. | 2014 Oct | 1 |
631 | 25258342 | IPI-145 antagonizes intrinsic and extrinsic survival signals in chronic lymphocytic leukemia cells. | 2014 Dec 4 | 1 |
632 | 25294819 | Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML. | 2014 Oct 30 | 2 |
633 | 25360238 | Bruton's tyrosine kinase inhibitors and their clinical potential in the treatment of B-cell malignancies: focus on ibrutinib. | 2014 Aug | 2 |
634 | 25361916 | Ibrutinib for the treatment of mantle cell lymphoma. | 2014 Nov 1 | 2 |
635 | 25696845 | BCR pathway inhibition as therapy for chronic lymphocytic leukemia and lymphoplasmacytic lymphoma. | 2014 Dec 5 | 1 |
636 | 22975686 | BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB. | 2013 Jan | 3 |
637 | 23045577 | Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B-cell malignancies. | 2013 Jan 1 | 4 |
638 | 23296407 | Ibrutinib (PCI-32765), the first BTK (Bruton's tyrosine kinase) inhibitor in clinical trials. | 2013 Mar | 3 |
639 | 23360303 | The Bruton tyrosine kinase (BTK) inhibitor PCI-32765 synergistically increases proteasome inhibitor activity in diffuse large-B cell lymphoma (DLBCL) and mantle cell lymphoma (MCL) cells sensitive or resistant to bortezomib. | 2013 Apr | 4 |
640 | 23672610 | Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases. | 2013 Aug | 2 |
641 | 23754751 | Dual phosphorylation of Btk by Akt/protein kinase b provides docking for 14-3-3ζ, regulates shuttling, and attenuates both tonic and induced signaling in B cells. | 2013 Aug | 2 |
642 | 23763320 | [Inhibition of B cell receptor signaling: a first targeted therapeutic approach for chronic lymphocytic leukemia and other B cell lymphomas]. | 2013 | 1 |
643 | 23782157 | Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma. | 2013 Aug 8 | 2 |
644 | 23782158 | Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia. | 2013 Jul 4 | 1 |
645 | 23940282 | Egress of CD19(+)CD5(+) cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients. | 2013 Oct 3 | 3 |
646 | 23954894 | Identification in CLL of circulating intraclonal subgroups with varying B-cell receptor expression and function. | 2013 Oct 10 | 1 |
647 | 23958373 | Ibrutinib and novel BTK inhibitors in clinical development. | 2013 Aug 19 | 1 |
648 | 23962569 | Bruton tyrosine kinase is commonly overexpressed in mantle cell lymphoma and its attenuation by Ibrutinib induces apoptosis. | 2013 Oct | 3 |
649 | 24014301 | Towards targeted therapy of chronic lymphocytic leukemia. | 2013 | 1 |
650 | 24083545 | The emerging role of ibrutinib in the treatment of chronic lymphocytic leukemia. | 2013 Oct | 2 |