Title : Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL.

Pub. Date : 2014 May 22

PMID : 24659631






1 Functional Relationships(s)
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1 We evaluated the in vivo effects of ibrutinib, a Bruton tyrosine kinase (BTK) inhibitor on tumor cell activation and proliferation in the blood, lymph node, and bone marrow of patients with CLL. ibrutinib Bruton tyrosine kinase Homo sapiens