Title : BCR pathway inhibition as therapy for chronic lymphocytic leukemia and lymphoplasmacytic lymphoma.

Pub. Date : 2014 Dec 5

PMID : 25696845






1 Functional Relationships(s)
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1 Ibrutinib, a covalent inhibitor of BTK approved by the Food and Drug Administration as a second-line treatment for CLL, and idelalisib, a selective inhibitor of PI3Kdelta, achieve excellent clinical responses in both diseases irrespective of classic markers indicating high-risk disease. ibrutinib Bruton tyrosine kinase Homo sapiens