Title : Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL).

Pub. Date : 2014 Feb 20

PMID : 24311722






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Bruton"s tyrosine kinase (BTK) shows constitutive activity in CLL and is the target of irreversible inhibition by ibrutinib, an orally bioavailable kinase inhibitor that has shown outstanding activity in CLL. ibrutinib Bruton tyrosine kinase Homo sapiens
2 Bruton"s tyrosine kinase (BTK) shows constitutive activity in CLL and is the target of irreversible inhibition by ibrutinib, an orally bioavailable kinase inhibitor that has shown outstanding activity in CLL. ibrutinib Bruton tyrosine kinase Homo sapiens