| 1 |
34890640 | Pirfenidone attenuates acetaminophen-induced liver injury via suppressing c-Jun N-terminal kinase phosphorylation. | 2022 Jan 1 |
4 |
| 2 |
35126160 | Atractylenolide I Ameliorates Acetaminophen-Induced Acute Liver Injury via the TLR4/MAPKs/NF-κB Signaling Pathways. | 2022 |
1 |
| 3 |
33290831 | Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice. | 2021 Mar 1 |
5 |
| 4 |
33435214 | Rutaecarpine Protects against Acetaminophen-Induced Acute Liver Injury in Mice by Activating Antioxidant Enzymes. | 2021 Jan 10 |
1 |
| 5 |
33458793 | Impaired protein adduct removal following repeat administration of subtoxic doses of acetaminophen enhances liver injury in fed mice. | 2021 Apr |
1 |
| 6 |
33460648 | Interaction of RIPK1 and A20 modulates MAPK signaling in murine acetaminophen toxicity. | 2021 Jan-Jun |
3 |
| 7 |
33840687 | Acetaminophen reduces osteoprotegerin synthesis stimulated by PGE2 and PGF2α in osteoblasts: attenuation of SAPK/JNK but not p38 MAPK or p44/p42 MAPK. | 2021 |
3 |
| 8 |
34311140 | Protective Role of microRNA-31 in Acetaminophen-Induced Liver Injury: A Negative Regulator of c-Jun N-Terminal Kinase (JNK) Signaling Pathway. | 2021 |
2 |
| 9 |
34750342 | CD5L deficiency attenuate acetaminophen-induced liver damage in mice via regulation of JNK and ERK signaling pathway. | 2021 Nov 8 |
1 |
| 10 |
34943052 | Downregulation of Glutathione-Mediated Detoxification Capacity by Binge Drinking Aggravates Acetaminophen-Induced Liver Injury through IRE1α ER Stress Signaling. | 2021 Dec 5 |
2 |
| 11 |
31705481 | BGP-15 Protects Mitochondria in Acute, Acetaminophen Overdose Induced Liver Injury. | 2020 Jul |
2 |
| 12 |
31945188 | c-Jun NH2 -Terminal Protein Kinase Phosphorylates the Nrf2-ECH Homology 6 Domain of Nuclear Factor Erythroid 2-Related Factor 2 and Downregulates Cytoprotective Genes in Acetaminophen-Induced Liver Injury in Mice. | 2020 May |
8 |
| 13 |
32171727 | Peroxiredoxin 6 mediates acetaminophen-induced hepatocyte death through JNK activation. | 2020 May |
3 |
| 14 |
32360799 | Oroxyloside ameliorates acetaminophen-induced hepatotoxicity by inhibiting JNK related apoptosis and necroptosis. | 2020 Aug 10 |
3 |
| 15 |
30260040 | Hydrogen sulfide protects against acetaminophen-induced acute liver injury by inhibiting apoptosis via the JNK/MAPK signaling pathway. | 2019 Mar |
4 |
| 16 |
30552702 | p53 Up-regulated Modulator of Apoptosis Induction Mediates Acetaminophen-Induced Necrosis and Liver Injury in Mice. | 2019 May |
1 |
| 17 |
30706943 | Mannan-binding lectin attenuates acetaminophen-induced hepatotoxicity by regulating CYP2E1 expression via ROS-dependent JNK/SP1 pathway. | 2019 Apr |
1 |
| 18 |
31076618 | A phospholipase D2 inhibitor, CAY10594, ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis. | 2019 May 10 |
3 |
| 19 |
31212965 | Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration. | 2019 Jun 17 |
1 |
| 20 |
31539158 | TLR4 promotes liver inflammation by activating the JNK pathway. | 2019 Sep |
2 |
| 21 |
31620005 | JNK Signaling Pathway Mediates Acetaminophen-Induced Hepatotoxicity Accompanied by Changes of Glutathione S-Transferase A1 Content and Expression. | 2019 |
12 |
| 22 |
31645120 | Carbon monoxide ameliorates acetaminophen-induced liver injury by increasing hepatic HO-1 and Parkin expression. | 2019 Dec |
1 |
| 23 |
31814709 | The MAP2K4/JNK/c-Jun Signaling Pathway Plays A Key Role In Dexmedetomidine Protection Against Acetaminophen-Induced Liver Toxicity. | 2019 |
1 |
| 24 |
31815033 | Chlorpromazine protects against acetaminophen-induced liver injury in mice by modulating autophagy and c-Jun N-terminal kinase activation. | 2019 Mar |
1 |
| 25 |
29425659 | Seabuckthorn berry polysaccharide extracts protect against acetaminophen induced hepatotoxicity in mice via activating the Nrf-2/HO-1-SOD-2 signaling pathway. | 2018 Jan 1 |
1 |
| 26 |
29574133 | Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice. | 2018 Jun 15 |
1 |
| 27 |
29943110 | Hepatocyte SHP deficiency protects mice from acetaminophen-evoked liver injury in a JNK-signaling regulation and GADD45β-dependent manner. | 2018 Aug |
2 |
| 28 |
30024038 | Glycycoumarin protects mice against acetaminophen-induced liver injury predominantly via activating sustained autophagy. | 2018 Oct |
1 |
| 29 |
28031524 | Adenosine 5'-monophosphate blocks acetaminophen toxicity by increasing ubiquitination-mediated ASK1 degradation. | 2017 Jan 24 |
2 |
| 30 |
28210203 | Wnt/β-Catenin Signaling Drives Thioacetamide-Mediated Heteroprotection Against Acetaminophen-Induced Lethal Liver Injury. | 2017 Jan-Mar |
4 |
| 31 |
28661486 | The role of MAP2 kinases and p38 kinase in acute murine liver injury models. | 2017 Jun 29 |
2 |
| 32 |
29217823 | Lysophosphatidic acid protects against acetaminophen-induced acute liver injury. | 2017 Dec 8 |
1 |
| 33 |
26708719 | Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury. | 2016 Apr |
5 |
| 34 |
26721299 | Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver. | 2016 Mar |
6 |
| 35 |
26807019 | Carnosic acid protects against acetaminophen-induced hepatotoxicity by potentiating Nrf2-mediated antioxidant capacity in mice. | 2016 Jan |
1 |
| 36 |
26972403 | Protective effect of apoptosis signal-regulating kinase 1 inhibitor against mice liver injury. | 2016 Mar |
1 |
| 37 |
27562556 | Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction. | 2016 Dec |
1 |
| 38 |
27891510 | Tropisetron Protects Against Acetaminophen-Induced Liver Injury via Suppressing Hepatic Oxidative Stress and Modulating the Activation of JNK/ERK MAPK Pathways. | 2016 |
2 |
| 39 |
25681557 | Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice. | 2015 Jul |
1 |
| 40 |
25818599 | Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury. | 2015 Jul 1 |
1 |
| 41 |
25884831 | Aminotriazole alleviates acetaminophen poisoning via downregulating P450 2E1 and suppressing inflammation. | 2015 |
1 |
| 42 |
25956474 | Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1-p53 signaling pathways. | 2015 Jul 16 |
1 |
| 43 |
26077809 | Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis. | 2015 Dec |
5 |
| 44 |
23873604 | Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through c-jun-N-terminal kinase (JNK)-dependent and -independent signaling pathways. | 2014 Apr |
7 |
| 45 |
24345528 | Protection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioning. | 2014 Feb 1 |
2 |
| 46 |
25218290 | Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase. | 2014 Nov 15 |
1 |
| 47 |
22986947 | Purinergic receptor antagonist A438079 protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation. | 2013 Jan |
4 |
| 48 |
23583805 | Davallialactone protects against acetaminophen overdose-induced liver injuries in mice. | 2013 Aug |
1 |
| 49 |
23697945 | Disruption of thioredoxin reductase 1 protects mice from acute acetaminophen-induced hepatotoxicity through enhanced NRF2 activity. | 2013 Jul 15 |
1 |
| 50 |
22124574 | Loss of autophagy promotes murine acetaminophen hepatotoxicity. | 2012 Apr |
3 |