Acetaminophen

mitogen-activated protein kinase 8 ; Mus musculus







69 Article(s)
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51 22623522 Mitogen-activated protein kinase phosphatase (Mkp)-1 protects mice against acetaminophen-induced hepatic injury. 2012 Dec 3
52 22687999 Resistance to acetaminophen-induced hepatotoxicity in glutathione S-transferase Mu 1-null mice. 2012 7
53 22918968 Critical role for mixed-lineage kinase 3 in acetaminophen-induced hepatotoxicity. 2012 Nov 9
54 23272189 Melatonin protects against apoptosis-inducing factor (AIF)-dependent cell death during acetaminophen-induced acute liver failure. 2012 2
55 21241727 The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity. 2011 Mar 15 1
56 21844199 c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice. 2011 Oct 7 3
57 20020266 Signal transduction pathways involved in drug-induced liver injury. 2010 4
58 20061376 Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1. 2010 Mar 12 4
59 20082487 Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway. 2010 Jan 21 1
60 20363829 Differential regulation of mitogen-activated protein kinase pathways by acetaminophen and its nonhepatotoxic regioisomer 3'-hydroxyacetanilide in TAMH cells. 2010 Jul 4
61 20371967 Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-alpha) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine hepatocytes. 2010 Apr 6
62 20539006 Diabetic KK-A(y) mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen. 2010 Aug 1
63 19589095 Acetaminophen and lipopolysaccharide act in synergy for the production of pro-inflammatory cytokines in murine RAW264.7 macrophages. 2009 Jun 1
64 18337250 Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury. 2008 May 16 17
65 18700144 Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation. 2008 Oct 1
66 17185352 Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure. 2007 Jul 10
67 17366662 Mitochondrial protection by the JNK inhibitor leflunomide rescues mice from acetaminophen-induced liver injury. 2007 Feb 4
68 16831600 c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity. 2006 Jul 1
69 17138759 Impact of Cu, Zn-superoxide dismutase and Se-dependent glutathione peroxidase-1 knockouts on acetaminophen-induced cell death and related signaling in murine liver. 2006 Dec 1