Pub. Date : 2020 Aug 10
PMID : 32360799
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oroxyloside ameliorates acetaminophen-induced hepatotoxicity by inhibiting JNK related apoptosis and necroptosis. | Acetaminophen | mitogen-activated protein kinase 8 | Mus musculus |
| 2 | In addition, oroxyloside inhibited the APAP-induced JNK related apoptosis by enhancing the antioxidant defenses, reversing ER-stress and keeping the mito-balance of liver cells in vivo and in vitro. | Acetaminophen | mitogen-activated protein kinase 8 | Mus musculus |
| 3 | CONCLUSION: Oroxyloside acted as a protective agent against APAP-induced liver injury through inhibiting JNK-related apoptosis and necroptosis. | Acetaminophen | mitogen-activated protein kinase 8 | Mus musculus |