Pub. Date : 2017 Jun 29
PMID : 28661486
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ROS production from mitochondria activates MAP3 kinases, such as MLK3 and ASK1, which continue to activate a pathway to sustain JNK activation, and amplifies the toxic effect of acetaminophen (APAP) and TNF/galactosamine (TNF/GalN). | Acetaminophen | mitogen-activated protein kinase 8 | Mus musculus |
| 2 | ROS production from mitochondria activates MAP3 kinases, such as MLK3 and ASK1, which continue to activate a pathway to sustain JNK activation, and amplifies the toxic effect of acetaminophen (APAP) and TNF/galactosamine (TNF/GalN). | Acetaminophen | mitogen-activated protein kinase 8 | Mus musculus |