Cholesterol

nuclear receptor subfamily 1, group H, member 3 ; Mus musculus







338 Article(s)
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1 34978526 Crocin ameliorates atherosclerosis by promoting the reverse cholesterol transport and inhibiting the foam cell formation via regulating PPARγ/LXR-α. 2022 Jan 1
2 34981658 Chronic Activation of LXRα Sensitizes Mice to Hepatocellular Carcinoma. 2022 May 2
3 35150895 Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis. 2022 Apr 1
4 35219337 LXR agonist improves peripheral neuropathy and modifies PNS immune cells in aged mice. 2022 Feb 26 2
5 35417135 Antihyperlipidemic Activity of Gut-Restricted LXR Inverse Agonists. 2022 May 20 3
6 35477277 Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis. 2022 Jun 2
7 32681027 Liver X receptor regulates Th17 and RORγt+ Treg cells by distinct mechanisms. 2021 Mar 2
8 32725442 PCSK9Qβ-003 Vaccine Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice. 2021 Feb 1
9 33050984 Combined application of rapamycin and atorvastatin improves lipid metabolism in apolipoprotein E-deficient mice with chronic kidney disease. 2021 Mar 1
10 33165140 Astragalin Retards Atherosclerosis by Promoting Cholesterol Efflux and Inhibiting the Inflammatory Response via Upregulating ABCA1 and ABCG1 Expression in Macrophages. 2021 Feb 1 1
11 33188828 Synthetic high-density lipoproteins delivering liver X receptor agonist prevent atherogenesis by enhancing reverse cholesterol transport. 2021 Jan 10 2
12 33200264 Liver X Receptor α in Sciatic Nerve Exerts an Alleviating Effect on Neuropathic Pain Behaviors Induced by Crush Injury. 2021 Feb 2
13 33305467 The roles of liver X receptor α in inflammation and inflammation-associated diseases. 2021 Jul 4
14 33619376 Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination. 2021 Feb 4
15 33666411 Liver X Receptor Activation with an Intranasal Polymer Therapeutic Prevents Cognitive Decline without Altering Lipid Levels. 2021 Mar 23 1
16 33692340 CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathway. 2021 Mar 10 2
17 33770194 Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction. 2021 Jul 2
18 33945906 IL-2Rβγ signalling in lymphocytes promotes systemic inflammation and reduces plasma cholesterol in atherosclerotic mice. 2021 Jun 1
19 34251816 LXR-Mediated Regulation of Marine-Derived Piericidins Aggravates High-Cholesterol Diet-Induced Cholesterol Metabolism Disorder in Mice. 2021 Jul 22 3
20 34281217 Muricholic Acids Promote Resistance to Hypercholesterolemia in Cholesterol-Fed Mice. 2021 Jul 2 1
21 34416392 Hepatic lysosomal acid lipase drives the autophagy-lysosomal response and alleviates cholesterol metabolic disorder in ApoE deficient mice. 2021 Dec 2
22 34481107 Liver X receptor beta deficiency attenuates autoimmune-associated neuroinflammation in a T cell-dependent manner. 2021 Nov 2
23 34485530 Morroniside Promotes PGC-1α-Mediated Cholesterol Efflux in Sodium Palmitate or High Glucose-Induced Mouse Renal Tubular Epithelial Cells. 2021 1
24 34564147 Saringosterol from Sargassum fusiforme Modulates Cholesterol Metabolism and Alleviates Atherosclerosis in ApoE-Deficient Mice. 2021 Aug 26 3
25 34564456 Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells. 2021 Sep 18 1
26 34568800 Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice. 2021 Sep 24 2
27 34686657 Smooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis. 2021 Oct 22 1
28 34753029 Qing-Xue-Xiao-Zhi formula attenuates atherosclerosis by inhibiting macrophage lipid accumulation and inflammatory response via TLR4/MyD88/NF-κB pathway regulation. 2021 Dec 2
29 34831289 Deletion of TSPO Causes Dysregulation of Cholesterol Metabolism in Mouse Retina. 2021 Nov 7 1
30 34926792 Self-Assembled Peptide Amphiphile Nanofibers for Controlled Therapeutic Delivery to the Atherosclerotic Niche. 2021 Sep 2
31 35082691 Expressing the Human Cholesteryl Ester Transfer Protein Minigene Improves Diet-Induced Fatty Liver and Insulin Resistance in Female Mice. 2021 1
32 31602646 Activation of liver X receptor promotes hippocampal neurogenesis and improves long-term cognitive function recovery in acute cerebral ischemia-reperfusion mice. 2020 Jul 1
33 31678621 Angiopoietin-1 aggravates atherosclerosis by inhibiting cholesterol efflux and promoting inflammatory response. 2020 Feb 1
34 31759199 Stigmasterol stimulates transintestinal cholesterol excretion independent of liver X receptor activation in the small intestine. 2020 Feb 2
35 31785104 Insights From Liver-Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR-Agonist Pharmacodynamics in Humans. 2020 Aug 1
36 31845693 Selenium alleviates lipopolysaccharide-induced endometritis via regulating the recruitment of TLR4 into lipid rafts in mice. 2020 Jan 29 1
37 31980500 Differential Role of Liver X Receptor (LXR) α and LXRβ in the Regulation of UDP-Glucuronosyltransferase 1A1 in Humanized UGT1 Mice. 2020 Apr 1
38 32037099 Dysregulation of LXR responsive genes contribute to ichthyosis in trichothiodystrophy. 2020 Mar 2
39 32329226 Complement Receptor Targeted Liposomes Encapsulating the Liver X Receptor Agonist GW3965 Accumulate in and Stabilize Atherosclerotic Plaques. 2020 May 2
40 32414201 LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction. 2020 May 13 2
41 32598492 Luteolin improves hypercholesterolemia and glucose intolerance through LXRα-dependent pathway in diet-induced obese mice. 2020 Sep 1
42 32641586 Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes. 2020 Jul 9 2
43 32661772 NPC1L1 and ABCG5/8 induction explain synergistic fecal cholesterol excretion in ob/ob mice co-treated with PPAR-α and LXR agonists. 2020 Oct 7
44 32736671 Macrophage Lxrα reduces atherosclerosis in Ldlr-/- mice independent of Arl7 transactivation. 2020 Aug 27 4
45 32779151 Setosphapyrone C and D accelerate macrophages cholesterol efflux by promoting LXRα/ABCA1 pathway. 2020 Aug 1
46 33050202 The Crucial Role of Xanthine Oxidase in CKD Progression Associated with Hypercholesterolemia. 2020 Oct 9 2
47 33098723 HDL cholesterol protects from liver injury in mice with intestinal specific LXRα activation. 2020 Dec 2
48 33190106 Regulation of intestinal LDLR by the LXR-IDOL axis. 2020 Dec 3
49 33292517 Iron accumulation in macrophages promotes the formation of foam cells and development of atherosclerosis. 2020 Nov 26 1
50 33390931 Synergetic Effect of rHDL and LXR Agonist on Reduction of Atherosclerosis in Mice. 2020 2