Title : Hepatic lysosomal acid lipase drives the autophagy-lysosomal response and alleviates cholesterol metabolic disorder in ApoE deficient mice.

Pub. Date : 2021 Dec

PMID : 34416392






2 Functional Relationships(s)
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1 Mechanically, hepatic LAL promoted cholesterol transport and biliary excretion by increasing liver X receptor alpha (LXRalpha) and its downstream genes, and modulated the compliance of the autophagy-lysosomal pathway. Cholesterol nuclear receptor subfamily 1, group H, member 3 Mus musculus
2 Mechanically, hepatic LAL promoted cholesterol transport and biliary excretion by increasing liver X receptor alpha (LXRalpha) and its downstream genes, and modulated the compliance of the autophagy-lysosomal pathway. Cholesterol nuclear receptor subfamily 1, group H, member 3 Mus musculus