Title : Muricholic Acids Promote Resistance to Hypercholesterolemia in Cholesterol-Fed Mice.

Pub. Date : 2021 Jul 2

PMID : 34281217






1 Functional Relationships(s)
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1 CONCLUSIONS: These coordinated events are mediated by increased muricholic acid levels which inhibit FXR signaling in favor of LXR and SREBP2 signaling to promote efficient fecal and urinary elimination of cholesterol and neo-synthesized bile acids. Cholesterol nuclear receptor subfamily 1, group H, member 3 Mus musculus