| 1 |
35067907 | An update on mode of action of metformin in modulation of meta-inflammation and inflammaging. | 2022 Apr |
4 |
| 2 |
35129424 | Identification of circular RNAs and functional competing endogenous RNA networks in human proximal tubular epithelial cells treated with sodium-glucose cotransporter 2 inhibitor dapagliflozin in diabetic kidney disease. | 2022 Feb |
1 |
| 3 |
35134125 | AMPK-mediated potentiation of GABAergic signalling drives hypoglycaemia-provoked spike-wave seizures. | 2022 Feb 3 |
1 |
| 4 |
35197629 | Low-dose metformin targets the lysosomal AMPK pathway through PEN2. | 2022 Mar |
8 |
| 5 |
35396800 | Biomimetic Nanocarriers Guide Extracellular ATP Homeostasis to Remodel Energy Metabolism for Activating Innate and Adaptive Immunity System. | 2022 Jun |
2 |
| 6 |
35431946 | Acute Administration of Metformin Protects Against Neuronal Apoptosis Induced by Cerebral Ischemia-Reperfusion Injury via Regulation of the AMPK/CREB/BDNF Pathway. | 2022 |
5 |
| 7 |
35459945 | At the crossroads of fertility and metabolism: the importance of AMPK-dependent signaling in female infertility associated with hyperandrogenism. | 2022 May 30 |
1 |
| 8 |
32386485 | Novel Targets of Metformin in Cardioprotection: Beyond the Effects Mediated by AMPK. | 2021 |
2 |
| 9 |
32940892 | Metformin Is Associated with Reduced Tissue Factor Procoagulant Activity in Patients with Poorly Controlled Diabetes. | 2021 Aug |
2 |
| 10 |
33161784 | Metformin as a potential therapeutic for neurological disease: mobilizing AMPK to repair the nervous system. | 2021 Jan |
5 |
| 11 |
33439105 | Metformin slows liver cyst formation and fibrosis in experimental model of polycystic liver disease. | 2021 Apr 1 |
1 |
| 12 |
33524789 | The effects of metformin on autophagy. | 2021 May |
8 |
| 13 |
33811249 | Metformin prevents stroke damage in non-diabetic female mice with chronic kidney disease. | 2021 Apr 2 |
2 |
| 14 |
33838154 | Metformin leads to accumulation of reactive oxygen species by inhibiting the NFE2L1 expression in human hepatocellular carcinoma cells. | 2021 Jun 1 |
6 |
| 15 |
33838541 | Narrative review of the influence of diabetes mellitus and hyperglycemia on colorectal cancer risk and oncological outcomes. | 2021 Jul |
1 |
| 16 |
33850550 | Metformin attenuates diabetic renal injury via the AMPK-autophagy axis. | 2021 Jun |
3 |
| 17 |
33915902 | Metformin Inhibits the Urea Cycle and Reduces Putrescine Generation in Colorectal Cancer Cell Lines. | 2021 Apr 1 |
2 |
| 18 |
33946426 | Metformin Dysregulates the Unfolded Protein Response and the WNT/β-Catenin Pathway in Endometrial Cancer Cells through an AMPK-Independent Mechanism. | 2021 Apr 30 |
3 |
| 19 |
34043989 | Therapeutic potential of AMPK signaling targeting in lung cancer: Advances, challenges and future prospects. | 2021 Aug 1 |
1 |
| 20 |
34046440 | AMPK: Potential Therapeutic Target for Vascular Calcification. | 2021 |
2 |
| 21 |
34115964 | Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation. | 2021 Jul 13 |
1 |
| 22 |
34156429 | The cellular pathways and potential therapeutics of Polycystic Kidney Disease. | 2021 Jun 30 |
1 |
| 23 |
34163481 | Metformin, Macrophage Dysfunction and Atherosclerosis. | 2021 |
2 |
| 24 |
34188521 | A Two-Stage Study Identifies Two Novel Polymorphisms in PRKAG2 Affecting Metformin Response in Chinese Type 2 Diabetes Patients. | 2021 |
1 |
| 25 |
34290400 | AMPK-deficiency forces metformin-challenged cancer cells to switch from carbohydrate metabolism to ketogenesis to support energy metabolism. | 2021 Sep |
5 |
| 26 |
34296521 | Metformin alleviates oxidative stress-induced senescence of human lens epithelial cells via AMPK activation and autophagic flux restoration. | 2021 Sep |
3 |
| 27 |
34396446 | Metformin inhibits cholesterol‑induced adhesion molecule expression via activating the AMPK signaling pathway in vascular smooth muscle cells. | 2021 Oct |
2 |
| 28 |
34421608 | Metformin Potentiates the Effects of Anlotinib in NSCLC via AMPK/mTOR and ROS-Mediated Signaling Pathways. | 2021 |
4 |
| 29 |
34434111 | Metformin Attenuates Silica-Induced Pulmonary Fibrosis by Activating Autophagy via the AMPK-mTOR Signaling Pathway. | 2021 |
3 |
| 30 |
34450310 | Activated AMPK by metformin protects against fibroblast proliferation during pulmonary fibrosis by suppressing FOXM1. | 2021 Nov |
4 |
| 31 |
34502359 | New Insight into the Effects of Metformin on Diabetic Retinopathy, Aging and Cancer: Nonapoptotic Cell Death, Immunosuppression, and Effects beyond the AMPK Pathway. | 2021 Aug 31 |
4 |
| 32 |
34514769 | Metformin - a new approach. | 2021 |
3 |
| 33 |
34517004 | Metformin attenuates the epithelial-mesenchymal transition of lens epithelial cells through the AMPK/TGF-β/Smad2/3 signalling pathway. | 2021 Nov |
1 |
| 34 |
34548527 | Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism. | 2021 Sep 21 |
3 |
| 35 |
34577590 | Metformin a Potential Pharmacological Strategy in Late Onset Alzheimer's Disease Treatment. | 2021 Sep 1 |
2 |
| 36 |
34588803 | Retarding Progression of Chronic Kidney Disease in Autosomal Dominant Polycystic Kidney Disease with Metformin and Other Therapies: An Update of New Insights. | 2021 |
2 |
| 37 |
34593558 | Modulation of Oxidative Phosphorylation with IM156 Attenuates Mitochondrial Metabolic Reprogramming and Inhibits Pulmonary Fibrosis. | 2021 Nov |
1 |
| 38 |
34772914 | Fatty acid transport protein-5 (FATP5) deficiency enhances hepatocellular carcinoma progression and metastasis by reprogramming cellular energy metabolism and regulating the AMPK-mTOR signaling pathway. | 2021 Nov 12 |
1 |
| 39 |
31654752 | Cetylpyridinium chloride is a potent AMP-activated kinase (AMPK) inducer and has therapeutic potential in cancer. | 2020 Jan |
1 |
| 40 |
32221038 | Metformin Enhances the Antitumor Activity of CD8+ T Lymphocytes via the AMPK-miR-107-Eomes-PD-1 Pathway. | 2020 May 1 |
2 |
| 41 |
32246808 | Activation of AMP-activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness. | 2020 May |
1 |
| 42 |
32281270 | Metformin suppresses proliferation and invasion of drug-resistant breast cancer cells by activation of the Hippo pathway. | 2020 May |
2 |
| 43 |
32312181 | Metformin and Inhibition of Transforming Growth Factor-Beta Stimulate In Vitro Transport in Primary Renal Tubule Cells. | 2020 Oct |
1 |
| 44 |
32347398 | Metformin ameliorates animal models of dermatitis. | 2020 Oct |
1 |
| 45 |
32364526 | Metformin: the updated protective property in kidney disease. | 2020 May 1 |
2 |
| 46 |
32453427 | AMP-activated protein kinase regulates alternative pre-mRNA splicing by phosphorylation of SRSF1. | 2020 Jun 26 |
1 |
| 47 |
32703218 | AMPK activation overcomes anti-EGFR antibody resistance induced by KRAS mutation in colorectal cancer. | 2020 Jul 23 |
2 |
| 48 |
32738111 | Metformin improves boar sperm quality via 5'-AMP-activated protein kinase-mediated energy metabolism in vitro. | 2020 Sep 18 |
7 |
| 49 |
32748028 | Evaluating the impact of AMPK activation, a target of metformin, on risk of cardiovascular diseases and cancer in the UK Biobank: a Mendelian randomisation study. | 2020 Nov |
8 |
| 50 |
32798506 | AMP-activated protein kinase: An attractive therapeutic target for ischemia-reperfusion injury. | 2020 Dec 5 |
1 |