Pub. Date : 2021 Sep 1
PMID : 34577590
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin, a first line antihyperglycemic medication, is a 5"-adenosine monophosphate (AMP)-activated protein kinase (AMPK) activator hypothesized to act as a geroprotective agent. | Metformin | protein kinase AMP-activated non-catalytic subunit beta 1 | Homo sapiens |
| 2 | Moreover, it has been recently demonstrated that metformin enhances synaptophysin, sirtuin-1, AMPK, and brain-derived neuronal factor (BDNF) immunoreactivity, which are essential markers of plasticity. | Metformin | protein kinase AMP-activated non-catalytic subunit beta 1 | Homo sapiens |