Pub. Date : 2021 Sep
PMID : 34296521
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin alleviates oxidative stress-induced senescence of human lens epithelial cells via AMPK activation and autophagic flux restoration. | Metformin | protein kinase AMP-activated non-catalytic subunit beta 1 | Homo sapiens |
| 2 | In addition, we showed that metformin alleviated the oxidative stress-induced senescence of HLE-B3 cells via the activation of AMPK. | Metformin | protein kinase AMP-activated non-catalytic subunit beta 1 | Homo sapiens |
| 3 | Subsequently, we found that metformin restored autophagic flux that had been impaired by oxidative stress by activating AMPK. | Metformin | protein kinase AMP-activated non-catalytic subunit beta 1 | Homo sapiens |