137 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
51 | 22281055 | Effects of hypoxic preconditioning on the expression of iron influx and efflux proteins in primary neuron culture. | 2012 Mar | 5 |
52 | 22453918 | The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1). | 2012 May 18 | 1 |
53 | 22938093 | Structures and mechanisms of antitumor agents: xestoquinones uncouple cellular respiration and disrupt HIF signaling in human breast tumor cells. | 2012 Sep 28 | 2 |
54 | 21368293 | Hypoxia. 5. Hypoxia and hematopoiesis. | 2011 Jun | 1 |
55 | 21861815 | Hypoxia inducible factor-1 as a target for neurodegenerative diseases. | 2011 | 1 |
56 | 21907923 | The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels. | 2011 Sep 13 | 1 |
57 | 19861159 | Oxygen-sensing under the influence of nitric oxide. | 2010 Mar | 2 |
58 | 20023006 | Iron chelator-mediated alterations in gene expression: identification of novel iron-regulated molecules that are molecular targets of hypoxia-inducible factor-1 alpha and p53. | 2010 Mar | 3 |
59 | 20095867 | Neuroprotective multifunctional iron chelators: from redox-sensitive process to novel therapeutic opportunities. | 2010 Sep 15 | 6 |
60 | 20416277 | Hinokitiol activates the hypoxia-inducible factor (HIF) pathway through inhibition of HIF hydroxylases. | 2010 May 28 | 1 |
61 | 20546814 | Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1 alpha and induction of autophagy in SH-SY5Y cells. | 2010 Oct | 5 |
62 | 20711226 | Hypoxia inducible factor 1 (HIF-1) and cardioprotection. | 2010 Sep | 2 |
63 | 20723262 | Effects of cellular iron deficiency on the formation of vascular endothelial growth factor and angiogenesis. Iron deficiency and angiogenesis. | 2010 Aug 19 | 4 |
64 | 20929261 | Mammea E/BB, an isoprenylated dihydroxycoumarin protonophore that potently uncouples mitochondrial electron transport, disrupts hypoxic signaling in tumor cells. | 2010 Nov 29 | 2 |
65 | 19074761 | Metal ions-stimulated iron oxidation in hydroxylases facilitates stabilization of HIF-1 alpha protein. | 2009 Feb | 3 |
66 | 19263519 | Manganese (II) induces chemical hypoxia by inhibiting HIF-prolyl hydroxylase: implication in manganese-induced pulmonary inflammation. | 2009 Mar 15 | 1 |
67 | 19384570 | Non-hypoxic stabilization of hypoxia-inducible factor alpha (HIF-alpha): relevance in neural progenitor/stem cells. | 2009 May | 2 |
68 | 19729006 | Hypoxia-inducible factor-1 (HIF-1) pathway activation by quercetin in human lens epithelial cells. | 2009 Dec | 1 |
69 | 17973296 | Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron. | 2008 Apr 15 | 4 |
70 | 18061585 | Flavonoids induce HIF-1alpha but impair its nuclear accumulation and activity. | 2008 Feb 15 | 2 |
71 | 18245813 | Iron depletion by deferoxamine up-regulates glucose uptake and insulin signaling in hepatoma cells and in rat liver. | 2008 Mar | 1 |
72 | 18261897 | DHEA decreases HIF-1alpha accumulation under hypoxia in human pulmonary artery cells: potential role in the treatment of pulmonary arterial hypertension. | 2008 Mar | 1 |
73 | 18371939 | Transplantation of human neural stem cells protect against ischemia in a preventive mode via hypoxia-inducible factor-1alpha stabilization in the host brain. | 2008 May 1 | 1 |
74 | 18385176 | Asbestos induces doxorubicin resistance in MM98 mesothelioma cells via HIF-1alpha. | 2008 Aug | 2 |
75 | 18459142 | PARP-1 modulates deferoxamine-induced HIF-1alpha accumulation through the regulation of nitric oxide and oxidative stress. | 2008 Aug 15 | 1 |
76 | 18538129 | Hypoxia upregulates the histone demethylase JMJD1A via HIF-1. | 2008 Aug 8 | 2 |
77 | 18559422 | Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia. | 2008 Aug | 1 |
78 | 18809098 | Erythropoietic agents and the elderly. | 2008 Oct | 1 |
79 | 19076458 | Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury. | 2008 Dec | 1 |
80 | 17364964 | The flavonoid quercetin induces hypoxia-inducible factor-1alpha (HIF-1alpha) and inhibits cell proliferation by depleting intracellular iron. | 2007 Mar | 1 |
81 | 17377063 | Quercetin activates an angiogenic pathway, hypoxia inducible factor (HIF)-1-vascular endothelial growth factor, by inhibiting HIF-prolyl hydroxylase: a structural analysis of quercetin for inhibiting HIF-prolyl hydroxylase. | 2007 Jun | 2 |
82 | 16139409 | Differential responses of two degradation domains of HIF-1alpha to hypoxia and iron deficiency. | 2006 Feb | 4 |
83 | 16510596 | Effects of transferrin receptor blockade on cancer cell proliferation and hypoxia-inducible factor function and their differential regulation by ascorbate. | 2006 Mar 1 | 1 |
84 | 16527254 | Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway. | 2006 Apr 28 | 3 |
85 | 16773207 | A domain responsible for HIF-1alpha degradation by YC-1, a novel anticancer agent. | 2006 Jul | 1 |
86 | 16842166 | Natural product-derived small molecule activators of hypoxia-inducible factor-1 (HIF-1). | 2006 | 1 |
87 | 16877034 | Effect of metal ions on HIF-1alpha and Fe homeostasis in human A549 cells. | 2006 Nov 7 | 2 |
88 | 17015263 | Cobalt induces hypoxia-inducible factor-1alpha (HIF-1alpha) in HeLa cells by an iron-independent, but ROS-, PI-3K- and MAPK-dependent mechanism. | 2006 Aug | 3 |
89 | 17100286 | [HIF-1alpha, HIF-2alpha and VHL mRNA expression in different cell lines during hypoxia]. | 2006 Mar-Apr | 1 |
90 | 17168739 | Role of HIF-1 in iron regulation: potential therapeutic strategy for neurodegenerative disorders. | 2006 Dec | 1 |
91 | 17178876 | Endothelins induce CCR7 expression by breast tumor cells via endothelin receptor A and hypoxia-inducible factor-1. | 2006 Dec 15 | 2 |
92 | 17190448 | Sodwanone and yardenone triterpenes from a South African species of the marine sponge Axinella inhibit hypoxia-inducible factor-1 (HIF-1) activation in both breast and prostate tumor cells. | 2006 Dec | 1 |
93 | 15538748 | Identification of hypoxia-inducible factor-1alpha (HIF-1alpha) polymorphism as a mutation in prostate cancer that prevents normoxia-induced degradation. | 2005 May 15 | 1 |
94 | 15749641 | [Hypoxia-inducible factor 1: regulation, involvement in carcinogenesis and target for anticancer therapy]. | 2005 Feb | 1 |
95 | 15777842 | The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL. | 2005 Mar 22 | 1 |
96 | 15878351 | Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron. | 2005 May 15 | 1 |
97 | 15885310 | Vascular endothelial growth factor is regulated by hypoxic stress via MAPK and HIF-1 alpha in the inner ear. | 2005 Jun | 1 |
98 | 15897903 | Accumulation of hypoxia-inducible factor-1alpha is limited by transcription-dependent depletion. | 2005 Jul 14 | 2 |
99 | 15913932 | Hypoxia-induced IL-6 production is associated with activation of MAP kinase, HIF-1, and NF-kappaB on HEI-OC1 cells. | 2005 Sep | 1 |
100 | 15923604 | Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling. | 2005 Jun | 1 |