| 1 |
35063568 | A tiered approach to investigate the inhalation toxicity of cobalt substances. Tier 2a: Grouping cobalt compounds based on their capacity to stabilize HIF-1α in human alveolar epithelial cells in vitro. | 2022 Apr |
1 |
| 2 |
32876363 | Cobalt-containing bioactive glass mimics vascular endothelial growth factor A and hypoxia inducible factor 1 function. | 2021 Jul |
3 |
| 3 |
33451366 | Bioactive glasses and electrospun composites that release cobalt to stimulate the HIF pathway for wound healing applications. | 2021 Jan 15 |
1 |
| 4 |
33838581 | Exosomes derived from macrophages upon cobalt ion stimulation promote angiogenesis. | 2021 Jul |
2 |
| 5 |
30508321 | Periprosthetic hypoxia as consequence of TRPM7 mediated cobalt influx in osteoblasts. | 2019 Aug |
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| 6 |
31533843 | HIF-1α is a key mediator of the lung inflammatory potential of lithium-ion battery particles. | 2019 Sep 18 |
2 |
| 7 |
29304733 | Cobalt chloride compromises transepithelial barrier properties of CaCo-2 BBe human gastrointestinal epithelial cell layers. | 2018 Jan 5 |
2 |
| 8 |
29456294 | Cobalt-containing bioactive glasses reduce human mesenchymal stem cell chondrogenic differentiation despite HIF-1α stabilisation. | 2018 Mar |
2 |
| 9 |
28004401 | Hypoxia-inducible factors as neuroprotective agent in Alzheimer's disease. | 2017 Mar |
1 |
| 10 |
26826385 | Cobalt chloride-mediated protein kinase Cα (PKCα) phosphorylation induces hypoxia-inducible factor 1α (HIF1α) in the nucleus of gastric cancer cell. | 2016 Feb 26 |
2 |
| 11 |
27132006 | Amperometric sensing of HIF1α expressed in cancer cells and the effect of hypoxic mimicking agents. | 2016 Sep 15 |
1 |
| 12 |
24277352 | Up-regulation of Gadd45α after exposure to metal nanoparticles: the role of hypoxia inducible factor 1α. | 2015 Apr |
1 |
| 13 |
25818442 | Hypoxia-mimicking bioactive glass/collagen glycosaminoglycan composite scaffolds to enhance angiogenesis and bone repair. | 2015 Jun |
1 |
| 14 |
24497960 | Cobalt and nickel stabilize stem cell transcription factor OCT4 through modulating its sumoylation and ubiquitination. | 2014 |
1 |
| 15 |
24611881 | Sorafenib blocks the HIF-1α/VEGFA pathway, inhibits tumor invasion, and induces apoptosis in hepatoma cells. | 2014 May |
1 |
| 16 |
23203800 | BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells. | 2013 Jan 15 |
2 |
| 17 |
23840602 | Cobalt-alloy implant debris induce HIF-1α hypoxia associated responses: a mechanism for metal-specific orthopedic implant failure. | 2013 |
2 |
| 18 |
23958427 | Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells. | 2013 Nov |
3 |
| 19 |
26105856 | OP0011. Impaired autophagy in extravillous trophoblast may induce poor placentation in preeclampsia. | 2013 Apr |
1 |
| 20 |
32260803 | Structural characterisation of hypoxia-mimicking bioactive glasses. | 2013 Mar 7 |
1 |
| 21 |
22177618 | Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering. | 2012 Mar |
2 |
| 22 |
22343435 | Activation of hypoxia-inducible factor by cobalt is associated with the attenuation of tissue injury and apoptosis in cyclosporine-induced nephropathy. | 2012 Mar |
1 |
| 23 |
22619252 | Copper is required for cobalt-induced transcriptional activity of hypoxia-inducible factor-1. | 2012 Aug |
6 |
| 24 |
21036805 | Inhibitory effect of extracellular histidine on cobalt-induced HIF-1alpha expression. | 2011 Feb |
2 |
| 25 |
20621833 | Glucose is necessary for stabilization of hypoxia-inducible factor-1alpha under hypoxia: contribution of the pentose phosphate pathway to this stabilization. | 2010 Jul 16 |
1 |
| 26 |
19128456 | Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis. | 2009 Jan 7 |
3 |
| 27 |
19396871 | Cobalt-induced oxidant stress in cultured endothelial cells: prevention by ascorbate in relation to HIF-1alpha. | 2009 May-Jun |
3 |
| 28 |
19457706 | Using YC-1 to overcome the radioresistance of hypoxic cancer cells. | 2009 Oct |
1 |
| 29 |
19714248 | Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha. | 2009 Aug 28 |
2 |
| 30 |
18202779 | Down-regulation of cobalt-induced HIF-1alpha expression correlates with cell proliferation and apoptosis in human gastric carcinoma cells. | 2008 Feb |
1 |
| 31 |
18473772 | Hypoxia inducible factor-1 alpha, endothelial progenitor cells, monocytes, cardiovascular risk, wound healing, cobalt and hydralazine: a unifying hypothesis. | 2008 May |
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| 32 |
17015263 | Cobalt induces hypoxia-inducible factor-1alpha (HIF-1alpha) in HeLa cells by an iron-independent, but ROS-, PI-3K- and MAPK-dependent mechanism. | 2006 Aug |
5 |
| 33 |
16249516 | Triamcinolone acetonide destabilizes VEGF mRNA in Müller cells under continuous cobalt stimulation. | 2005 Nov |
2 |
| 34 |
16705796 | Down-regulation of the expression of the FIH-1 and ARD-1 genes at the transcriptional level by nickel and cobalt in the human lung adenocarcinoma A549 cell line. | 2005 Apr |
2 |
| 35 |
14726713 | HIF-1: an oxygen and metal responsive transcription factor. | 2004 Jan |
1 |
| 36 |
15048879 | Sp1-dependent regulation of the tissue inhibitor of metalloproteinases-1 promoter. | 2004 Apr 15 |
1 |
| 37 |
15147973 | Bisphenol A, an environmental endocrine-disrupting chemical, inhibits hypoxic response via degradation of hypoxia-inducible factor 1alpha (HIF-1alpha): structural requirement of bisphenol A for degradation of HIF-1alpha. | 2004 Jun 11 |
2 |
| 38 |
12810083 | pVHL-independent ubiquitination of HIF1alpha and its stabilization by cobalt ion. | 2003 Jul 4 |
2 |
| 39 |
11779168 | Cobalt- and nickel-binding property of cullin-2. | 2002 Jan 11 |
2 |
| 40 |
11886167 | Stabilization of hypoxia-inducible factor-1alpha is involved in the hypoxic stimuli-induced expression of vascular endothelial growth factor in osteoblastic cells. | 2002 Jan 7 |
3 |
| 41 |
11286986 | Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells. | 2001 Apr 15 |
1 |
| 42 |
11358837 | Dynamic, site-specific interaction of hypoxia-inducible factor-1alpha with the von Hippel-Lindau tumor suppressor protein. | 2001 May 15 |
2 |
| 43 |
11739637 | A new HIF-1 alpha variant induced by zinc ion suppresses HIF-1-mediated hypoxic responses. | 2001 Nov |
2 |
| 44 |
10679259 | Zinc induces the accumulation of hypoxia-inducible factor (HIF)-1alpha, but inhibits the nuclear translocation of HIF-1beta, causing HIF-1 inactivation. | 2000 Feb 16 |
1 |
| 45 |
10866824 | Cadmium blocks hypoxia-inducible factor (HIF)-1-mediated response to hypoxia by stimulating the proteasome-dependent degradation of HIF-1alpha. | 2000 Jul |
1 |
| 46 |
10939628 | Regulation of endothelin-1 gene expression in human microvascular endothelial cells by hypoxia and cobalt: role of hypoxia responsive element. | 2000 May |
1 |
| 47 |
9510530 | Erythropoietin: a model system for studying oxygen-dependent gene regulation. | 1998 Apr |
1 |
| 48 |
7836384 | Purification and characterization of hypoxia-inducible factor 1. | 1995 Jan 20 |
2 |