Title : Periprosthetic hypoxia as consequence of TRPM7 mediated cobalt influx in osteoblasts.

Pub. Date : 2019 Aug

PMID : 30508321






1 Functional Relationships(s)
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1 This study shows that chemical hypoxia originating from HIF-1alpha upregulation within the periprosthetic tissue is related to cobalt wear debris and highlights TRPM7 as an important key mediator in this context. Cobalt hypoxia inducible factor 1 subunit alpha Homo sapiens