Glucose

hypoxia inducible factor 1 subunit alpha ; Homo sapiens







265 Article(s)
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1 34651203 HIF-1 mediated activation of antimicrobial peptide LL-37 in type 2 diabetic patients. 2022 Jan 1
2 34872812 Treatment with the Prolyl Hydroxylase Inhibitor JNJ Promotes Abdominal Aortic Aneurysm Progression in Diabetic Mice. 2022 Mar 1
3 35088883 High‑glucose microenvironment promotes perineural invasion of pancreatic cancer via activation of hypoxia inducible factor 1α. 2022 Apr 2
4 35189090 Inhibition of abnormally activated HIF-1α-GLUT1/3-glycolysis pathway enhances the sensitivity of hepatocellular carcinoma to 5-caffeoylquinic acid and its derivatives. 2022 Apr 5 1
5 35348849 Lipid metabolic reprogramming by hypoxia-inducible factor-1 in the hypoxic tumour microenvironment. 2022 Jun 1
6 35412588 Interferon-a potentiates anti-PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment. 2022 Apr 12 2
7 35415942 Effect of Glut-1 and HIF-1α double knockout by CRISPR/CAS9 on radiosensitivity in laryngeal carcinoma via the PI3K/Akt/mTOR pathway. 2022 May 1
8 35432450 Therapeutic Targeting Hypoxia-Inducible Factor (HIF-1) in Cancer: Cutting Gordian Knot of Cancer Cell Metabolism. 2022 2
9 35576836 SIRT5 is involved in the proliferation and metastasis of breast cancer by promoting aerobic glycolysis. 2022 Jul 3
10 32551804 FDG PET correlates weakly with HIF-1α expression in solid tumors: a meta-analysis. 2021 Apr 1
11 33359671 Balanophorin B inhibited glycolysis with the involvement of HIF-1α. 2021 Feb 15 1
12 33401572 Flavonoids Targeting HIF-1: Implications on Cancer Metabolism. 2021 Jan 3 2
13 33520443 Identification of a novel association for the WWOX/HIF1A axis with gestational diabetes mellitus (GDM). 2021 2
14 33624591 [Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells via stabilization of HIF-1α]. 2021 Feb 25 1
15 33649449 Development of antitumor biguanides targeting energy metabolism and stress responses in the tumor microenvironment. 2021 Mar 1 2
16 33754057 A novel role of kallikrein-related peptidase 8 in the pathogenesis of diabetic cardiac fibrosis. 2021 1
17 34108057 Prognostic significance of hypoxia-inducible factor-1α expression in advanced pharyngeal cancer without human papillomavirus infection. 2021 Jul 1
18 34178852 The rate of aerobic glycolysis is a pivotal regulator of tumor progression. 2021 Jun 1
19 34193173 STAT3/HIF-1α signaling activation mediates peritoneal fibrosis induced by high glucose. 2021 Jun 30 3
20 34196069 The transcription factor TEAD4 enhances lung adenocarcinoma progression through enhancing PKM2 mediated glycolysis. 2021 Oct 1
21 34326958 Decarboxylated osteocalcin, a possible drug for type 2 diabetes, triggers glucose uptake in MG63 cells. 2021 Jul 15 1
22 34426491 Elevated glucose increases genomic instability by inhibiting nucleotide excision repair. 2021 Oct 1
23 34447462 MicroRNA-18a-5p regulates the Warburg effect by targeting hypoxia-inducible factor 1α in the K562/ADM cell line. 2021 Oct 1
24 34479471 HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury. 2021 Sep 3 6
25 34558885 Diallyl Trisulfide Suppresses High-Glucose-Induced Cardiomyocyte Apoptosis by Targeting Reactive Oxygen Species-Mediated Hypoxia-Inducible Factor-1α/Insulin-like Growth Factor Binding Protein 3 Activation. 2021 Oct 6 2
26 34572324 Normalizing HIF-1α Signaling Improves Cellular Glucose Metabolism and Blocks the Pathological Pathways of Hyperglycemic Damage. 2021 Sep 2 1
27 34575914 Paricalcitol Improves Hypoxia-Induced and TGF-β1-Induced Injury in Kidney Pericytes. 2021 Sep 9 1
28 34692517 Counteracting Action of Curcumin on High Glucose-Induced Chemoresistance in Hepatic Carcinoma Cells. 2021 1
29 34736121 Metformin reduces macrophage HIF1α-dependent proinflammatory signaling to restore brown adipocyte function in vitro. 2021 Oct 19 2
30 34759325 Hyperglycemia-induced accumulation of advanced glycosylation end products in fibroblast-like synoviocytes promotes knee osteoarthritis. 2021 Nov 1
31 34820369 HIF1 and ID1 Interplay Confers Adaptive Survival to HIF1α-Inhibition. 2021 3
32 34948094 Transcription Factor ChREBP Mediates High Glucose-Evoked Increase in HIF-1α Content in Epithelial Cells of Renal Proximal Tubules. 2021 Dec 10 10
33 34992822 Succinate dehydrogenase 5 regulates lung cancer metastasis by reprogramming glucose metabolism. 2021 Nov 1
34 31720731 Activation of the HIF1α/PFKFB3 stress response pathway in beta cells in type 1 diabetes. 2020 Jan 1
35 31944299 The Shc protein Rai enhances T-cell survival under hypoxia. 2020 Nov 1
36 32045650 Hypoxia increases the rate of renal gluconeogenesis via hypoxia-inducible factor-1-dependent activation of phosphoenolpyruvate carboxykinase expression. 2020 Apr - May 3
37 32152275 HIF1A activates the transcription of lncRNA RAET1K to modulate hypoxia-induced glycolysis in hepatocellular carcinoma cells via miR-100-5p. 2020 Mar 9 1
38 32158929 How to starve cancer cells when nutrients are abundant. 2020 1
39 32200037 hENT1 reverses chemoresistance by regulating glycolysis in pancreatic cancer. 2020 Jun 1 1
40 32222493 GSK343, an inhibitor of EZH2, mitigates fibrosis and inflammation mediated by HIF-1α in human peritoneal mesothelial cells treated with high glucose. 2020 Aug 5 1
41 32241009 Competing Effects of Renin Angiotensin System Blockade and Sodium-Glucose Cotransporter-2 Inhibitors on Erythropoietin Secretion in Diabetes. 2020 2
42 32412317 Effect of low dose of berberine on the radioresistance of cervical cancer cells via a PI3K/HIF-1 pathway under nutrient-deprived conditions. 2020 Aug 1
43 32606855 Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha. 2020 1
44 32680978 Circular RNA circVEGFC accelerates high glucose-induced vascular endothelial cells apoptosis through miR-338-3p/HIF-1α/VEGFA axis. 2020 Jul 17 1
45 32697943 Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis. 2020 Sep 1 1
46 32809974 Hypoxia-inducible factors and diabetes. 2020 Oct 1 2
47 32877692 Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis. 2020 Sep 1 1
48 32984331 Baicalein and Baicalin Promote Melanoma Apoptosis and Senescence via Metabolic Inhibition. 2020 1
49 33126773 Pulsed Electromagnetic Fields Stimulate HIF-1α-Independent VEGF Release in 1321N1 Human Astrocytes Protecting Neuron-Like SH-SY5Y Cells from Oxygen-Glucose Deprivation. 2020 Oct 28 1
50 33282728 HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation. 2020 1