Pub. Date : 2021
PMID : 33520443
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Background: Although the WW-domain-containing oxidoreductase (WWOX)/Hypoxia-inducible factor 1 (HIF1) pathway is a well-known regulator of cellular glucose and energy metabolism in pathophysiological processes, its role in gestational diabetes mellitus (GDM), remains elusive. | Glucose | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
2 | Quantitative RT-PCR was performed to determine gene expression profiles of the WWOX/HIF1A-related genes, including those involved in glucose transport (SLC2A1, SLC2A4), glycolytic pathway (HK2, PKM2, PFK, LDHA), Wnt pathway (DVL2, CTNNB1), and inflammatory response (NFKB1). | Glucose | hypoxia inducible factor 1 subunit alpha | Homo sapiens |